采用新型重组融合蛋白酶联免疫吸附测定法确定的幼儿人偏肺病毒和呼吸道合胞病毒血清流行病学。
Seroepidemiologies of human metapneumovirus and respiratory syncytial virus in young children, determined with a new recombinant fusion protein enzyme-linked immunosorbent assay.
作者信息
Dunn Sarah R, Ryder Alex B, Tollefson Sharon J, Xu Meng, Saville Benjamin R, Williams John V
机构信息
Departments of Pediatrics.
出版信息
Clin Vaccine Immunol. 2013 Oct;20(10):1654-6. doi: 10.1128/CVI.00750-12. Epub 2013 Aug 14.
Abstract
We compared antibodies against human metapneumovirus (HMPV) and respiratory syncytial virus (RSV) in children. The antibody nadirs for both viruses were at 3 to 5 months, and the majority of children were seropositive for both by 2 years. There was no significant difference in the kinetics of maternal antibody decline or seroconversion relative to the two viruses.
摘要
我们比较了儿童体内抗人偏肺病毒（HMPV）和呼吸道合胞病毒（RSV）的抗体。两种病毒的抗体最低点均出现在3至5个月时，到2岁时，大多数儿童对这两种病毒的血清学检测均呈阳性。相对于这两种病毒，母体抗体下降或血清转化的动力学没有显著差异。
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