在德国波恩所研究的所有年龄组中，针对人偏肺病毒的中和能力血清阳性率很高。
High seroprevalence of neutralizing capacity against human metapneumovirus in all age groups studied in Bonn, Germany.
作者信息
Lüsebrink Jessica, Wiese Christoph, Thiel Anne, Tillmann Ramona-Liza, Ditt Vanessa, Müller Andreas, Schildgen Oliver, Schildgen Verena
机构信息
Institute for Virology, University of Bonn Medical Centre, Bonn, Germany.
出版信息
Clin Vaccine Immunol. 2010 Mar;17(3):481-4. doi: 10.1128/CVI.00398-09. Epub 2009 Dec 30.
Abstract
Human metapneumovirus (hMPV) infections occur frequently despite high rates of perpetual seroprevalence for all age groups. Analyses of approximately 2,000 archived, randomly selected serum samples demonstrated that neutralizing capacities remain high, with a minor decrease for individuals over 69 years of age, leading to the hypothesis that reinfections occur because humoral immune responses play minor roles in the clearance of hMPV infections.
摘要
尽管所有年龄组的永久血清阳性率很高，但人偏肺病毒（hMPV）感染仍频繁发生。对大约2000份随机选取的存档血清样本进行分析表明，中和能力仍然很高，69岁以上个体的中和能力略有下降，这导致了一种假设，即再次感染会发生是因为体液免疫反应在清除hMPV感染中起的作用较小。
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