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高速光学相干断层扫描作为一种可靠的辅助工具用于对眼前房炎症进行分级。

High-speed optical coherence tomography as a reliable adjuvant tool to grade ocular anterior chamber inflammation.

作者信息

Igbre Ann O, Rico Mario C, Garg Sunir J

机构信息

*Department of Ophthalmology, and †Sol Sherry Thrombosis Center, Temple University School of Medicine, Philadelphia, Pennsylvania; and ‡MidAtlantic Retina, The Retina Service of Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.

出版信息

Retina. 2014 Mar;34(3):504-8. doi: 10.1097/IAE.0b013e31829f73bd.

Abstract

PURPOSE

To evaluate the high-speed anterior segment optical coherence tomography (AS-OCT) grading of the AS inflammation in patients with ocular inflammation.

METHODS

A retrospective consecutive case series study. Patients with clinically visible AS inflammation in at least one eye underwent AS-OCT (Visante; Zeiss Meditec) with three to eight line scans per eye, performed by a trained masked examiner. The images were reviewed for hyperreflective spots, noise, and artifact, and these were correlated to clinical examination.

RESULTS

Seventy-eight eyes of 41 patients were imaged. Forty-seven eyes had anterior chamber cells on clinical examination, and 68 had hyperreflective spots visible on AS-OCT. There was a significant correlation (Spearman r = 0.7274) between clinical examination and Visante OCT images. Several patterns of inflammation and artifacts were apparent.

CONCLUSION

The AS-OCT is a promising technique for grading anterior chamber cells. There was a significant correlation between clinical examination and Visante grading.

摘要

目的

评估眼部炎症患者眼前节炎症的高速眼前节光学相干断层扫描(AS-OCT)分级。

方法

一项回顾性连续病例系列研究。至少一只眼睛有临床可见眼前节炎症的患者接受了AS-OCT(Visante;蔡司医疗技术公司)检查,由一名经过培训的盲法检查者对每只眼睛进行三到八次线扫描。对图像进行高反射点、噪声和伪像检查,并将这些与临床检查结果相关联。

结果

对41例患者的78只眼睛进行了成像。47只眼睛在临床检查中有前房细胞,68只眼睛在AS-OCT上可见高反射点。临床检查与Visante OCT图像之间存在显著相关性(Spearman r = 0.7274)。几种炎症和伪像模式明显。

结论

AS-OCT是一种有前景的前房细胞分级技术。临床检查与Visante分级之间存在显著相关性。

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