Department of Ophthalmology, Ophthalmic laboratory of Molecular Medicine Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
J Clin Sleep Med. 2013 Aug 15;9(8):741-5. doi: 10.5664/jcsm.2908.
To evaluate whether blue-light-blocking intraocular lens implantation affects the sleep quality of cataract patients.
Pre-test/post-test experiment.
N/A.
40 patients having bilateral cataracts with level higher than N3 (LOCS II) nucleus hardness, including 26 females (65%) and 14 males (35%).
Cataract phacoemulsification followed by blue-light-blocking intraocular lens (IOLs, SN60WF, Alcon Laboratories, USA) implantation.
Patients were contacted in site before cataract surgery and followed by telephone at least 2 months later after second-eye surgery. Pittsburgh Sleep Quality Index (PSQI) questionnaires were administered to evaluate sleep quality. Median age of patients was 74 years (IQR 70 to 78). The median PSQI globe scores were 7 before surgery and 4 after surgery (Z = -2.121, p = 0.037). More specifically, there were significant differences on subjective sleep quality (Z = -2.064, p = 0.045), sleep duration (Z = -2.037, p = 0.047) and daytime dysfunction (Z = -2.142, p = 0.034) when compared between before and after surgeries. The ratio of poor sleepers (PSQI > 5) was reduced significantly after surgery (χ² = 14.532, p < 0.001).
Blue-light-blocking IOL had a significantly beneficial effect on the sleep quality of cataract patients.
评估蓝光阻断型人工晶状体植入是否会影响白内障患者的睡眠质量。
预测试/后测试实验。
无。
40 名双眼患有核硬度高于 N3(LOCS II)级别的白内障患者,其中 26 名女性(65%),14 名男性(35%)。
白内障超声乳化术联合蓝光阻断型人工晶状体(IOL,SN60WF,Alcon Laboratories,美国)植入术。
患者在白内障手术前在现场联系,并在双眼手术后至少 2 个月后通过电话进行随访。采用匹兹堡睡眠质量指数(PSQI)问卷评估睡眠质量。患者的中位年龄为 74 岁(IQR 70 至 78)。PSQI 总分中位数在术前为 7 分,术后为 4 分(Z = -2.121,p = 0.037)。更具体地说,与术前相比,术后主观睡眠质量(Z = -2.064,p = 0.045)、睡眠持续时间(Z = -2.037,p = 0.047)和日间功能障碍(Z = -2.142,p = 0.034)均有显著差异。术后睡眠质量差(PSQI>5)的比例显著降低(χ² = 14.532,p < 0.001)。
蓝光阻断型人工晶状体对白内障患者的睡眠质量有显著的有益影响。