为有丝分裂做准备。
PREEParing for mitosis.
机构信息
Institute of Medical Biology, 8A Biomedical Grove, Immunos, Singapore.
出版信息
Dev Cell. 2013 Aug 12;26(3):221-2. doi: 10.1016/j.devcel.2013.07.018.
PMID:23948250
Abstract
Reporting in Developmental Cell, Schlaitz et al. (2013) show that endoplasmic reticulum (ER) membrane exclusion from the mitotic spindle is an active process requiring REEP membrane proteins. REEP protein depletion results in ER membrane retention on the spindle and chromosomes, leading to defects in chromosome segregation and nuclear envelope assembly.
摘要
施莱特等人在《发育细胞》杂志上的报告（2013 年）表明，内质网（ER）膜从有丝分裂纺锤体中排除是一个需要 REEP 膜蛋白的主动过程。REEP 蛋白耗竭导致 ER 膜在纺锤体和染色体上的保留，导致染色体分离和核膜组装缺陷。
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