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锂相关性甲状腺功能亢进症

Lithium-associated hyperthyroidism.

作者信息

Siyam Fadi F, Deshmukh Sanaa, Garcia-Touza Mariana

机构信息

Division of Endocrinology, Diabetes, and Metabolism.

出版信息

Hosp Pract (1995). 2013 Aug;41(3):101-4. doi: 10.3810/hp.2013.08.1073.

Abstract

Goiters and hypothyroidism are well-known patient complications of the use of lithium for treatment of bipolar disease. However, the occurrence of lithium-induced hyperthyroidism is a more rare event. Many times, the condition can be confused with a flare of mania. Monitoring through serial biochemical measurement of thyroid function is critical in patients taking lithium. Hyperthyroidism induced by lithium is a condition that generally can be controlled medically without the patient having to discontinue lithium therapy, although in some circumstances, discontinuation of lithium therapy may be indicated. We report on a patient case of lithium-associated hyperthyroidism that resolved after discontinuation of the medication.

摘要

甲状腺肿和甲状腺功能减退是使用锂盐治疗双相情感障碍时常见的患者并发症。然而,锂盐诱发的甲状腺功能亢进症则较为罕见。很多时候,这种情况可能会与躁狂发作相混淆。对于服用锂盐的患者,通过连续生化检测甲状腺功能进行监测至关重要。锂盐诱发的甲状腺功能亢进症通常可以通过药物控制,患者无需停用锂盐治疗,不过在某些情况下,可能需要停用锂盐治疗。我们报告了一例停用药物后锂盐相关性甲状腺功能亢进症得以缓解的患者病例。

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