Durmus Dilek, Uzuner Bora, Durmaz Yunus, Bilgici Ayhan, Kuru Omer
Department of Physical Medicine and Rehabilitation, Medical Faculty, Ondokuz Mayis University, Samsun, Turkey.
J Back Musculoskelet Rehabil. 2013;26(4):467-73. doi: 10.3233/BMR-130408.
The aim of this study was to investigate the clinical relevance of Michigan Hand Outcomes Questionnaire (MHQ) in patients with rheumatoid arthritis (RA) and to evaluate the relationship between MHQ and disease activity, quality of life (QL), and handgrip strength separately.
Eighty RA were included in the study. Disease activity is evaluated with Disease Activity Score 28 (DAS28), pain is evaluated with Visual Analog Scale (VAS). The Disabilities of Arm, Shoulder and Hand (DASH), MHQ, Short-Form 36 (SF-36), and Health Assessment Questionnaire (HAQ), Arthritis Impact Measurement Scales-hand and finger function scale-2 (AIMS-2) were completed by all patients. Hand muscle strength (HMS) was measured with a hand-held dynamometer.
The MHQ moderately correlated with DAS28. When the patients were grouped according to three disease activity measurements, DASH scores were significantly higher with higher disease activity and MHQ scores were significantly lower with higher disease activity. A high correlation was found between MHQ total and HAQ, AIMS-2. The SF-36 scores were correlated with MHQ scores.
The MHQ scores correlate with disease activity indices, functional disability, QL and DASH. The clinical relevance of MHQ, like DASH, is high and both questionnaires can be used effectively.
本研究旨在调查密歇根手部结果问卷（MHQ）在类风湿关节炎（RA）患者中的临床相关性，并分别评估MHQ与疾病活动度、生活质量（QL）和握力之间的关系。
80例RA患者纳入本研究。采用疾病活动度评分28（DAS28）评估疾病活动度，采用视觉模拟量表（VAS）评估疼痛程度。所有患者均完成上肢、肩部和手部功能障碍量表（DASH）、MHQ、简明健康状况调查问卷（SF-36）、健康评估问卷（HAQ）、关节炎影响测量量表-手部和手指功能量表2（AIMS-2）。使用手持式测力计测量手部肌肉力量（HMS）。
MHQ与DAS28呈中度相关。根据三种疾病活动度测量结果对患者进行分组时，疾病活动度越高，DASH评分越高，而MHQ评分越低。发现MHQ总分与HAQ、AIMS-2高度相关。SF-36评分与MHQ评分相关。
MHQ评分与疾病活动指数、功能残疾、QL和DASH相关。与DASH一样，MHQ的临床相关性较高，两种问卷均可有效使用。
