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多发性硬化症患者住院接受多学科康复治疗的益处。

Benefits of inpatient multidisciplinary rehabilitation in multiple sclerosis.

机构信息

Department of Neurology, Medical University of Vienna, Vienna, Austria.

出版信息

NeuroRehabilitation. 2013;33(2):285-92. doi: 10.3233/NRE-130956.

Abstract

BACKGROUND

Rehabilitation is often recommended to MS-patients but data on its efficacy is limited.

OBJECTIVE

To evaluate the benefit of inpatient multidisciplinary rehabilitation.

METHODS

A rater-blinded, randomized, waiting list controlled exploratory study. 19 participants completed the study with ten allocated to the intervention and nine to the waiting list group. Assessment of outcome-parameters was done at baseline and after 3 months. Time Walking Tests (TWTs) and 9 Hole Peg Test were used to objectively assess the level of activity, Functional-Assessment-in-MS and MS-Self Efficacy-Scale to assess participation and quality of life and Expanded Disability Status Scale (EDSS) to assess bodily function. Additionally Rivermead Mobility Index, Berg Balance Scale, Tinetti-Test, MS-Functional Composite and a rater-blinded evaluation of a video-analysis on walking performance was done.

RESULTS

Mean change scores of Timed 50 meter Walk (p = 0.014), walking speed (p = 0.034), 2- (p = 0.204) and 6-Minute Walk (p = 0.027) indicated an improvement favoring inpatient multidisciplinary rehabilitation. We could not demonstrate a benefit for upper limb function and some improvement was seen in other outcome-parameters without reaching statistical significance. EDSS remained unchanged.

CONCLUSION

Inpatient multidisciplinary rehabilitation is effective in MS patients with positive impact on the level of activity as measured by TWTs covering both short and long distance ambulation.

摘要

背景

康复常常被推荐给多发性硬化症(MS)患者,但关于其疗效的数据有限。

目的

评估住院多学科康复的益处。

方法

这是一项盲法、随机、等待名单对照的探索性研究。19 名参与者完成了研究,其中 10 名分配到干预组,9 名分配到等待名单组。在基线和 3 个月后评估结局参数。时间步行测试(TWT)和 9 孔钉测试用于客观评估活动水平,功能评估多发性硬化症量表和多发性硬化症自我效能量表用于评估参与度和生活质量,扩展残疾状况量表(EDSS)用于评估身体功能。此外,还进行了Rivermead 移动指数、Berg 平衡量表、Tinetti 测试、多发性硬化症功能综合评估以及对步行表现的视频分析进行了盲法评估。

结果

定时 50 米走(p = 0.014)、行走速度(p = 0.034)、2 分钟(p = 0.204)和 6 分钟步行(p = 0.027)的平均变化分数表明住院多学科康复有改善的趋势。我们未能证明上肢功能的益处,其他一些结局参数也有所改善,但没有达到统计学意义。EDSS 保持不变。

结论

住院多学科康复对多发性硬化症患者有效,对 TWT 测量的活动水平有积极影响,包括短距离和长距离步行。

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