Zebrafish Neurogenetics, Neurobiologie et Développement, Insitut de Neurobiologie Albert Fessard, Centre National de la Recherche Scientifique, Gif-sur-Yvette, Essonne, France.
PLoS One. 2013 Aug 9;8(8):e70172. doi: 10.1371/journal.pone.0070172. eCollection 2013.
Zebrafish exhibit remarkable alterations in behaviour and morphology as they develop from early larval stages to mature adults. In this study we compare the locomotion parameters of six common zebrafish strains from two different laboratories to determine the stability and repeatability of these behaviours. Our results demonstrate large variability in locomotion and fast swim events between strains and between laboratories across time. These data highlight the necessity for careful, strain-specific controls when analysing locomotor phenotypes and open up the possibility of standardising the quantification of zebrafish behaviour at multiple life stages.
斑马鱼从早期幼虫发育到成熟成鱼时，其行为和形态会发生显著变化。在这项研究中，我们比较了来自两个不同实验室的六个常见斑马鱼品系的运动参数，以确定这些行为的稳定性和可重复性。我们的研究结果表明，不同品系之间以及不同实验室之间的运动和快速游泳事件存在很大的变异性。这些数据强调了在分析运动表型时需要进行仔细的、特定于品系的对照，并为在多个生命阶段标准化斑马鱼行为的定量分析提供了可能性。
