Raucci-Neto Walter, de Castro-Raucci Larissa Moreira Spinola, Lepri Cesar Penazzo, Faraoni-Romano Juliana Jendiroba, Gomes da Silva Jaciara Miranda, Palma-Dibb Regina Guenka
Department of Restorative Dentistry, Ribeirão Preto Dental School, University of São Paulo, Avenida do Café, s/nº, Monte Alegre, CEP 14040-904, Ribeirão Preto, SP, Brazil,
Lasers Med Sci. 2015 Feb;30(2):761-8. doi: 10.1007/s10103-013-1417-z. Epub 2013 Aug 17.
Dental caries is still the most prevalent chronic disease affecting human populations. Among the preventive treatments performed, it has been reported that laser irradiation combined with topical fluoride can induce an even greater increase in enamel caries resistance. The aim of this study was to evaluate the Nd:YAG laser, with or without fluoride, in occlusal caries prevention of the primary dentition. A double-blind split-mouth study design was used. Fifty-two children with high caries risk (7.6 ± 1.4 years) were selected and received the following: G1--the first molar was a negative control, and the second received a resin sealant; G2--the first molar was a negative control, and the second received laser irradiation (50 mJ, 10 Hz, 0.5 W); G3--the first molar received only acidulate phosphate fluoride (APF), and the second received APF + laser; G4--fisrt molar received only fluoride varnish, and the second received fluoride varnish + laser. Patients were followed up to 12 months to evaluate the presence of white-spot lesions and/or caries cavities by three calibrated observers. Thirty-five patients completed the study. Significant differences were found between the treatment and control groups (p < 0.05). The laser-alone and resin sealant resulted in statistically lower caries formation than the negative control group (p < 0.05). Nd:YAG laser irradiation in primary teeth effectively prevented occlusal caries in pits and fissures when used alone with lower energy over a 1-year period.
龋齿仍然是影响人类的最普遍的慢性疾病。在已开展的预防性治疗中，据报道激光照射联合局部用氟可使牙釉质抗龋能力得到更大程度的提高。本研究的目的是评估钕钇铝石榴石（Nd:YAG）激光单独或联合氟化物在预防乳牙咬合面龋齿方面的效果。采用双盲、半口研究设计。选取52名高龋风险儿童（7.6±1.4岁），并给予以下治疗：G1组——第一磨牙为阴性对照，第二磨牙接受树脂封闭剂；G2组——第一磨牙为阴性对照，第二磨牙接受激光照射（50 mJ，10 Hz，0.5 W）；G3组——第一磨牙仅接受酸性磷酸氟（APF），第二磨牙接受APF+激光；G4组——第一磨牙仅接受氟保护漆，第二磨牙接受氟保护漆+激光。由三名经过校准的观察者对患者进行为期12个月的随访，以评估白斑病变和/或龋洞的存在情况。35名患者完成了研究。治疗组与对照组之间存在显著差异（p<0.05）。单独使用激光和树脂封闭剂导致的龋齿形成在统计学上低于阴性对照组（p<0.05）。在1年的时间里，单独使用低能量的Nd:YAG激光照射可有效预防乳牙窝沟龋的发生。
