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单价流感 A(H1N1)pdm09 疫苗预防经反转录聚合酶链反应确诊的大流行流感住院的有效性：美国 10 个流感监测网络点的儿童和成人病例对照研究。

Effectiveness of nonadjuvanted monovalent influenza A(H1N1)pdm09 vaccines for preventing reverse transcription polymerase chain reaction-confirmed pandemic influenza hospitalizations: case-control study of children and adults at 10 US influenza surveillance network sites.

机构信息

Influenza Division, Centers for Disease Control and Prevention.

出版信息

Clin Infect Dis. 2013 Dec;57(11):1587-92. doi: 10.1093/cid/cit551. Epub 2013 Aug 15.

DOI:10.1093/cid/cit551
PMID:23956169
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7314184/
Abstract

During 2009-2010, we examined 217 patients hospitalized with laboratory-confirmed pandemic influenza in 9 Influenza Hospitalization Surveillance Network sites and 413 age- and community-matched controls and found that a single dose of monovalent nonadjuvanted influenza A(H1N1)pdm09 vaccine was 50% (95% confidence interval, 13%-71%) effective in preventing hospitalization associated with A(H1N1)pdm09 virus infection.

摘要

在 2009-2010 年期间，我们在 9 个流感住院监测网络点和 413 名年龄和社区匹配的对照中检查了 217 名经实验室确诊的大流行性流感住院患者，发现单剂单价无佐剂流感 A(H1N1)pdm09 疫苗预防与 A(H1N1)pdm09 病毒感染相关的住院的有效性为 50%（95%置信区间，13%-71%）。