Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
J Infect Dis. 2012 Nov;206(9):1350-8. doi: 10.1093/infdis/jis517. Epub 2012 Sep 21.
The Emerging Infections Programs (EIP) network has conducted population-based surveillance for hospitalizations due to laboratory-confirmed influenza among children since 2003, with the network expanding in 2005 to include adults.
From 15 April 2009 through 30 April 2010, the EIP conducted surveillance among 22.1 million people residing in 10 states. Incidence rates per 100 000 population were calculated using US Census Bureau data. Mean historic rates were calculated on the basis of previously published and unpublished EIP data.
During the 2009 pandemic of influenza A virus subtype H1N1 infection, rates of hospitalizations due to laboratory-confirmed influenza were 202, 88, 49, 31, 27, 36, 28, and 27 episodes per 100 000 among persons aged <6 months, 6-23 months, 2-4 years, 5-17 years, 18-49 years, 50-64 years, 65-74 years, and ≥75 years, respectively. Comparative mean rates from previous influenza seasons during which EIP conducted surveillance were 153, 53, 20, 6, 4, 8, 20, and 56 episodes per 100 000 among persons aged <6 months, 6-23 months, 2-4 years, 5-17 years, 18-49 years, 50-64 years, 65-74 years, and ≥75 years, respectively.
During the pandemic, rates of hospitalization due to laboratory-confirmed influenza among individuals aged 5-17 years and 18-49 years increased 5-fold and 6-fold, respectively, compared with mean rates from previous influenza seasons. Hospitalization rates for other pediatric and adult age groups increased, compared with mean rates from previous influenza seasons, whereas the rate among individuals aged ≥75 years decreased.
自 2003 年以来,新兴传染病项目(EIP)网络一直在进行基于人群的住院监测,以监测实验室确诊的儿童流感,该网络于 2005 年扩大到包括成年人。
从 2009 年 4 月 15 日至 2010 年 4 月 30 日,EIP 在 10 个州对 2210 万人进行了监测。每 10 万人的发病率使用美国人口普查局的数据计算。平均历史发病率是根据以前发表和未发表的 EIP 数据计算的。
在 2009 年甲型 H1N1 流感大流行期间,实验室确诊流感导致的住院率分别为每 10 万人<6 个月、6-23 个月、2-4 岁、5-17 岁、18-49 岁、50-64 岁、65-74 岁和≥75 岁的 202、88、49、31、27、36、28 和 27 例。与 EIP 进行监测的前几个流感季节的比较平均发病率分别为每 10 万人<6 个月、6-23 个月、2-4 岁、5-17 岁、18-49 岁、50-64 岁、65-74 岁和≥75 岁的 153、53、20、6、4、8、20 和 56 例。
在大流行期间,与前几个流感季节的平均发病率相比,5-17 岁和 18-49 岁人群因实验室确诊流感而住院的比例分别增加了 5 倍和 6 倍。与前几个流感季节的平均发病率相比,其他儿科和成年年龄组的住院率有所增加,而≥75 岁人群的住院率则有所下降。