Birmingham & Solihull Mental Health Foundation Trust, Research & Innovation Department, Radclyffe House, 66-68 Hagley Road, Birmingham B16 8PF, UK.
Trials. 2013 Aug 19;14:264. doi: 10.1186/1745-6215-14-264.
Research indicates that 3% of people receiving opiate substitution treatment (OST) in the UK manage to achieve abstinence from all prescribed and illicit drugs within 3 years of commencing treatment, and there is concern that treatment services have become skilled at engaging people but not at helping them to enter a stage of recovery and drug abstinence. The National Treatment Agency for Substance Misuse recommends the involvement of families and wider social networks in supporting drug users' psychological treatment, and this pilot randomized controlled trial aims to evaluate the impact of a social network-focused intervention for patients receiving OST.
In this two-site, early phase, randomized controlled trial, a total of 120 patients receiving OST will be recruited and randomized to receive one of three treatments: 1) Brief Social Behavior and Network Therapy (B-SBNT), 2) Personal Goal Setting (PGS) or 3) treatment as usual. Randomization will take place following baseline assessment. Participants allocated to receive B-SBNT or PGS will continue to receive the same treatment that is routinely provided by drug treatment services, plus four additional sessions of either intervention. Outcomes will be assessed at baseline, 3 and 12 months. The primary outcome will be assessment of illicit heroin use, measured by both urinary analysis and self-report. Secondary outcomes involve assessment of dependence, psychological symptoms, social satisfaction, motivation to change, quality of life and therapeutic engagement. Family members (n = 120) of patients involved in the trial will also be assessed to measure the level of symptoms, coping and the impact of the addiction problem on the family member at baseline, 3 and 12 months.
This study will provide experimental data regarding the feasibility and efficacy of implementing a social network intervention within routine drug treatment services in the UK National Health Service. The study will explore the impact of the intervention on both patients receiving drug treatment and their family members.
ISRCTN22608399. ISRCTN22608399 registration: 27/04/2012. Date of first randomisation: 14/08/2012.
研究表明，在英国接受阿片类药物替代治疗（OST）的人群中，有 3%的人在开始治疗的 3 年内成功戒除所有规定和非法药物，人们担心治疗服务已经擅长让人们参与，但不擅长帮助他们进入康复和戒除药物的阶段。国家药物滥用治疗机构建议让家庭和更广泛的社交网络参与支持吸毒者的心理治疗，这项试点随机对照试验旨在评估针对接受 OST 的患者的以社交网络为重点的干预措施的影响。
在这项两地点、早期阶段、随机对照试验中，将招募 120 名接受 OST 的患者，并将他们随机分配接受以下三种治疗之一：1）简短社交行为和网络治疗（B-SBNT），2）个人目标设定（PGS）或 3）常规治疗。随机化将在基线评估后进行。分配接受 B-SBNT 或 PGS 的参与者将继续接受药物治疗服务常规提供的相同治疗，外加另外四次干预。结果将在基线、3 个月和 12 个月时进行评估。主要结果将是通过尿液分析和自我报告评估非法海洛因使用情况。次要结果包括评估依赖、心理症状、社交满意度、改变动机、生活质量和治疗参与度。参与试验的患者的家庭成员（n=120）也将进行评估，以衡量基线、3 个月和 12 个月时家庭成员的症状、应对方式和成瘾问题对家庭成员的影响。
这项研究将提供有关在英国国民保健制度常规药物治疗服务中实施社交网络干预措施的可行性和疗效的实验数据。该研究将探讨干预措施对接受药物治疗的患者及其家庭成员的影响。
ISRCTN22608399。ISRCTN22608399 注册：2012 年 4 月 27 日。首次随机分组日期：2012 年 8 月 14 日。
