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盆腔系统的三维模拟数值模拟,以更好地理解子宫韧带的作用。

3D simulation of pelvic system numerical simulation for a better understanding of the contribution of the uterine ligaments.

作者信息

Rubod C, Lecomte-Grosbras P, Brieu M, Giraudet G, Betrouni N, Cosson M

机构信息

Gynaecology Department, Jeanne de Flandre Hospital, CHRU LILLE-Lille Nord University, 59000, Lille, France,

出版信息

Int Urogynecol J. 2013 Aug 20. doi: 10.1007/s00192-013-2135-6.

Abstract

INTRODUCTION AND HYPOTHESIS

Genital prolapse remains a complex pathological condition. Physiopathology remains poorly understood, aetiology is multi-factorial, surgery is not always satisfying, as the rate of relapse cannot be overlooked. More over a good anatomical result will not always guarantee functional satisfaction. The aim of our study is to have a better understanding of the involvement of uterine ligaments in pelvic statics via 3D simulation.

METHODS

Simulation of pelvic mobility is performed with a validated numerical model in a normal situation (standing up to lying down) or induced pathological ones where parts of the constitutive elements of the model are virtually "cut" independently. Displacements are then discussed.

RESULTS

Numerical results have been compared with dynamic MRI for two volunteers. Dynamic sequences had 90 images, and 180 simulations have been validated. Results are coherent with clinical data and the literature, thus validating our mechanical approach. Uterine ligaments are involved in pelvic statics, but their lesions are not sufficient to generate a genital prolapse. Round ligaments play a part in uterine orientation; the utero-sacral ligaments support the uterus when standing up.

CONCLUSIONS

Pelvic normal and pathological mobility study via modelling and 3D simulation is a new strategy in understanding the complex multifactorial physiopathology of genital prolapse. This approach must be validated in a larger series of patients. Nevertheless, pelvic ligaments seem to play an important role in statics, especially, in agreement with a literature survey, utero-sacral ligaments in a standing position.

摘要

引言与假设

生殖器脱垂仍然是一种复杂的病理状况。其病理生理学仍未得到充分理解,病因是多因素的,手术效果并不总是令人满意,因为复发率不容忽视。此外,良好的解剖学结果并不总能保证功能上的满意度。我们研究的目的是通过三维模拟更好地了解子宫韧带在盆腔静力学中的作用。

方法

使用经过验证的数值模型模拟盆腔在正常情况(从站立到躺下)或诱导的病理情况下的活动,在诱导的病理情况下,模型的组成部分会被虚拟地独立“切断”。然后讨论位移情况。

结果

对两名志愿者的数值结果与动态磁共振成像进行了比较。动态序列有90张图像,180次模拟得到了验证。结果与临床数据和文献一致,从而验证了我们的力学方法。子宫韧带参与盆腔静力学,但它们的损伤不足以导致生殖器脱垂。圆韧带在子宫定位中起作用;骶子宫韧带在站立时支撑子宫。

结论

通过建模和三维模拟研究盆腔正常和病理活动是理解生殖器脱垂复杂多因素病理生理学的一种新策略。这种方法必须在更多患者中得到验证。然而,盆腔韧带似乎在静力学中起重要作用,特别是根据文献调查,骶子宫韧带在站立位时。

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