基于偶氮苯对底物结合亲和力的调控实现单分子光驱动 DNA 纳米剪刀对 DNA 的切割
Single-molecule photon-fueled DNA nanoscissors for DNA cleavage based on the regulation of substrate binding affinity by azobenzene.
机构信息
The Key Laboratory of Analytical Science, Key Laboratory for Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
出版信息
Chem Commun (Camb). 2013 Oct 7;49(77):8716-8. doi: 10.1039/c3cc44188a.
PMID:23958857
Abstract
A pair of single-molecule photo-responsive DNA nanoscissors for DNA cleavage based on the regulation of substrate binding affinity was designed and fabricated. Compared with other DNA nanomachines, our DNA nanoscissors have the advantages of a clean switching mechanism, as well as robust and highly reversible operation.
摘要
设计并制造了一种基于底物结合亲和力调控的用于 DNA 切割的双单分子光响应 DNA 纳米剪刀。与其他 DNA 纳米机器相比，我们的 DNA 纳米剪刀具有清洁的开关机制以及稳健且高度可逆的操作等优点。
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