Mattes R
Monell Chemical Senses Center, Philadelphia, PA 19104.
Physiol Behav. 1990 Jun;47(6):1037-44. doi: 10.1016/0031-9384(90)90350-d.
Physiological and behavioral responses to high intensity sweeteners have been poorly characterized, leading to questions regarding their utility in weight management regimens. To address this issue, studies must independently control attributes such as the taste properties, chemical composition and energy contribution of a given sweetener, as well as subject expectations of its effects. In the present study, 24 adults of normal weight consumed breakfasts including unsweetened or sweetened (sucrose or aspartame) cereal for 5 days, during which hunger and energy intake were monitored. The cereals were rated as equally sweet and pleasant and were equicaloric. Half of the subjects were aware of the cereal composition. Neither sweet taste nor aspartame alone significantly affected reported hunger, daily energy intake or subsequent selection of foods with varying taste qualities. Energy intake tended to be more strongly influenced by perceptions of the energy value of the experimental breakfast. Thus, this study failed to find an appetite stimulating effect of either sweetness or sweetener (aspartame or sucrose).
对高强度甜味剂的生理和行为反应一直缺乏充分的描述，这引发了关于它们在体重管理方案中的效用的疑问。为了解决这个问题，研究必须独立控制诸如给定甜味剂的味道特性、化学成分和能量贡献等属性，以及受试者对其效果的预期。在本研究中，24名体重正常的成年人连续5天食用包含无糖或加糖（蔗糖或阿斯巴甜）谷物的早餐，在此期间监测饥饿感和能量摄入。这些谷物被评为甜度和口感相同且热量相等。一半的受试者知道谷物的成分。单独的甜味或阿斯巴甜均未显著影响报告的饥饿感、每日能量摄入或随后对不同口味食物的选择。能量摄入似乎更多地受到对实验性早餐能量值认知的强烈影响。因此，本研究未能发现甜味或甜味剂（阿斯巴甜或蔗糖）有刺激食欲的作用。
