Rogers P J, Carlyle J A, Hill A J, Blundell J E
Psychology Department, University of Leeds, U.K.
Physiol Behav. 1988;43(5):547-52. doi: 10.1016/0031-9384(88)90207-7.
This study was carried out to disclose effects generated by the uncoupling of the sensory and energetic components of sweet solutions. A comparison was made between equi-sweet preloads of three intense sweeteners (saccharin, aspartame and acesulfame-K), a bulk sweetener (glucose) and a nonsweet water control. Measures were made of subjective ratings of motivation to eat, food preferences and energy intake in a test meal. The glucose load produced a consistent pattern of changes on all measures. The intense sweeteners tended to facilitate motivational ratings and food preference checklist responses, but marginally lowered intake in the test meal. The facilitative action is probably due to the stimulation of sensory receptors for sweetness by the high-intensity agents, while the effects on intake are most likely due to a ceiling effect imposed by methodological limitations of this particular design. The results of this study must be interpreted with reference to the prevailing experimental conditions, but they suggest that intense sweeteners can produce significant changes in appetite. Of the intense sweeteners, aspartame gave rise to the most pronounced effects.
本研究旨在揭示甜味溶液的感官成分与能量成分解偶联所产生的影响。对三种高强度甜味剂（糖精、阿斯巴甜和安赛蜜-K）、一种填充甜味剂（葡萄糖）和一种非甜味水对照的等甜度预负荷进行了比较。在一顿测试餐中，对进食动机的主观评分、食物偏好和能量摄入进行了测量。葡萄糖负荷在所有测量指标上都产生了一致的变化模式。高强度甜味剂倾向于提高动机评分和食物偏好清单反应，但在测试餐中的摄入量略有降低。促进作用可能是由于高强度甜味剂对甜味感觉受体的刺激，而对摄入量的影响很可能是由于这种特定设计的方法学局限性所产生的上限效应。本研究结果必须结合当前的实验条件来解释，但它们表明高强度甜味剂可显著改变食欲。在高强度甜味剂中，阿斯巴甜产生的影响最为显著。
