Balasch J
Departamento de Obstetricia y Ginecología, Facultad de Medicina, Hospital Clínico i Provincial, Barcelona, Spain.
Rev Esp Fisiol. 1990 Mar;46(1):79-82.
As a bioassay of the steroidogenic function of the corpus luteum, endometrial biopsy has been proposed as the most efficient way of diagnosing corpus luteum insufficiency. However, analysis of our data on luteal phase evaluation in infertility shows that most cases (86%) of endometrial luteal inadequacy are associated with normal hormone (progesterone, estradiol) stimulation. This apparent lack of endometrial progestational response may be explained by an end organ defect localized to the endometrial steroid receptors.
作为黄体类固醇生成功能的生物测定方法，子宫内膜活检已被认为是诊断黄体功能不全最有效的方法。然而，对我们关于不孕症患者黄体期评估的数据进行分析后发现，大多数（86%）子宫内膜黄体功能不足的病例与正常的激素（孕酮、雌二醇）刺激有关。这种明显缺乏子宫内膜孕激素反应的情况可能是由子宫内膜类固醇受体局部的终末器官缺陷所解释的。
