Department of Neurosurgery, Kyungpook National University Hospital, Daegu, Korea.
J Korean Med Sci. 2013 Aug;28(8):1253-6. doi: 10.3346/jkms.2013.28.8.1253. Epub 2013 Jul 31.
Intramedullary spinal cord metastasis (ISCM) from renal cell carcinoma (RCC) is rare manifestation and most of them are treated by adjuvant treatment modalities like radiotherapy. Despite the radio-resistance of RCC itself, focal radiotherapy has been preferred as the first-line treatment modality of ISCM from RCC and only a few cases underwent surgical treatment. We describe a case of ISCM from RCC, which underwent surgical excision and pathologically confirmed. A 44-yr-old man was presented with rapid deterioration of motor weakness during focal radiotherapy for ISCM from RCC. After the surgery for removal of the tumor mass and spinal cord decompression, his motor power was dramatically improved to ambulate by himself. We report the first published Korean case of ISCM from RCC confirmed pathologically and describe our surgical experience and his clinical characteristics.
脊髓内转移瘤(ISCM)来自肾细胞癌(RCC)是一种罕见的表现,大多数采用辅助治疗方法,如放疗。尽管 RCC 本身具有放射抗性,但局部放疗一直是 RCC 来源的 ISCM 的一线治疗方法,只有少数情况下进行手术治疗。我们描述了一例 RCC 来源的 ISCM 病例,该病例经过手术切除并经病理证实。一名 44 岁男性在因 RCC 来源的 ISCM 进行局部放疗期间,出现运动无力迅速恶化。在肿瘤切除和脊髓减压手术后,他的运动能力显著提高,可以自行行走。我们报告了首例经病理证实的韩国 RCC 来源的 ISCM 病例,并描述了我们的手术经验和他的临床特征。