Pahwa Narinder, Kumar Atul, Gupta Siddharth
Department of Orthodontics, S.B.B. Dental College, Ghaziabad, India.
Saudi Dent J. 2011 Jul;23(3):135-41. doi: 10.1016/j.sdentj.2011.03.001. Epub 2011 Apr 13.
To test the short term clinical effectiveness of commercially available 0.07%.cetylpyridinium chloride mouth rinse in patients undergoing fixed orthodontic treatment as compared to a placebo mouth rinse and patients using toothbrush and toothpaste.
Forty-five subjects for this double blind study were assigned randomly into three groups of 15 each. Gingival inflammation, plaque accumulation, and bleeding on probing, were recorded at baseline (10 days after prophylaxis), and at the end of one month in all the three groups and compared.
Paired t test showed significant differences in bleeding index for pre and post treatment recordings for cetylpyridinium group. Modified gingival index showed no significant difference in the cetylpyridinium group. For plaque index significant difference was found for cetylpyridinium and control groups.
Cetylpyridinium mouth rinse 0.7% was found to be effective in reducing the bleeding and plaque index scores. It was not effective in reducing the modified gingival index scores. Cetylpyridinium mouth rinse 0.07% improves the oral hygiene of orthodontic patients when used as an adjunct to normal oral hygiene measures.
与安慰剂漱口水以及使用牙刷和牙膏的患者相比，测试市售0.07%西吡氯铵漱口水在接受固定正畸治疗患者中的短期临床疗效。
这项双盲研究的45名受试者被随机分为三组，每组15人。在基线期（预防性治疗后10天）以及所有三组治疗一个月结束时，记录牙龈炎症、牙菌斑积聚和探诊出血情况，并进行比较。
配对t检验显示西吡氯铵组治疗前后记录的出血指数存在显著差异。改良牙龈指数在西吡氯铵组中无显著差异。对于菌斑指数，西吡氯铵组和对照组存在显著差异。
发现0.7%西吡氯铵漱口水在降低出血和菌斑指数评分方面有效。它在降低改良牙龈指数评分方面无效。0.07%西吡氯铵漱口水作为正常口腔卫生措施的辅助手段使用时，可改善正畸患者的口腔卫生。
