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沙特阿拉伯利雅得一家教学医院中毒的模式和决定因素。

Pattern and determinants of poisoning in a teaching hospital in Riyadh, Saudi Arabia.

机构信息

School of Pharmacy, Taif University, P.O. Box 1347, Saudi Arabia.

出版信息

Saudi Pharm J. 2011 Jan;19(1):57-63. doi: 10.1016/j.jsps.2010.10.002. Epub 2010 Nov 4.

Abstract

BACKGROUND

The Drug and Poison Information Center (DPIC) at King Khalid University Hospital, Riyadh, Saudi Arabia, was founded in 1983. Since then it has responded adequately to queries from medical and non-medical callers from all over the Kingdom. Queries ranged from simple material identification to poisoning cases.

OBJECTIVES

To assess the pattern and circumstances of poisoning in the Kingdom of Saudi Arabia through reviewing data from DPIC in King Khalid University hospitals.

METHODS

This is a retrospective study of referred cases and calls received by DPIC. All records and documentation forms during the study period were investigated.

RESULTS

This study included 1161 cases. There were 7.9% infants, 52.9% under 5 years old, 7.2% between 6-12 years old and 32.0% more than 12 years old. Number of males with toxic exposure was almost equal to that of females. More than 92% of cases were toxic exposure through oral route. Causes of poisoning include drugs among 76.7% of cases followed by household chemicals (6.8%). Suicidal intention was reported among 25.6% of cases. Using multivariate regression analysis, significant predictors of suicidal attempts are more than 12 years old, patients who were exposed to more than one toxin and patient who came to the hospital within 1-3 h since poisoning.

RECOMMENDATIONS

Establishing and operating DPIC centers throughout the kingdom, in addition to implementing of legislations to ban over the counter selling of medications and to sell potentially dangerous chemicals in childproof containers.

摘要

背景

沙特阿拉伯利雅得的哈立德国王大学医院的药物和毒物信息中心(DPIC)成立于 1983 年。自那时以来,它已经充分响应了来自王国各地的医疗和非医疗呼叫者的查询。查询范围从简单的物质识别到中毒案例。

目的

通过审查 DPIC 在哈立德国王大学医院收到的来自王国的中毒数据,评估沙特阿拉伯的中毒模式和情况。

方法

这是 DPIC 转介病例和来电的回顾性研究。研究期间调查了所有记录和文件表格。

结果

这项研究包括 1161 例病例。有 7.9%的婴儿,52.9%的年龄在 5 岁以下,7.2%的年龄在 6-12 岁之间,32.0%的年龄在 12 岁以上。有毒物质暴露的男性人数几乎与女性人数相等。超过 92%的病例是通过口服途径接触毒物。中毒原因包括 76.7%的病例中的药物,其次是家用化学品(6.8%)。有 25.6%的病例报告有自杀意图。使用多元回归分析,自杀企图的显著预测因素是年龄超过 12 岁、接触一种以上毒素的患者和中毒后 1-3 小时内到医院就诊的患者。

建议

在王国各地建立和运营 DPIC 中心,此外还应实施立法,禁止非处方药和以儿童防护容器出售潜在危险化学品。

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