1974 - 1981年纽卡斯尔儿童中毒情况的变化模式
Changing pattern of poisoning in children in Newcastle, 1974-81.
作者信息
Lawson G R, Craft A W, Jackson R H
出版信息
Br Med J (Clin Res Ed). 1983 Jul 2;287(6384):15-7. doi: 10.1136/bmj.287.6384.15.
All children aged under 15 years admitted to hospital in Newcastle upon Tyne between 1974 and 1981 with a diagnosis of poisoning were studied. After the introduction in 1976 of child resistant containers for salicylates and paracetamol, salicylate poisonings fell dramatically. The other most important medicines to cause poisoning in young children were tricyclic antidepressants, benzodiazapines, Lomotil (diphenoxylate and atropine), and iron preparations; these should also be packaged in child resistant containers by regulation. Few children had symptoms after poisoning with household products, but bleach, turpentine, and paraffin might also be packaged in child resistant containers. The numbers of adolescent girls admitted after deliberate self poisoning and of teenage boys admitted after ingestion of alcohol increased over the study period.
对1974年至1981年间在泰恩河畔纽卡斯尔住院的所有15岁以下诊断为中毒的儿童进行了研究。1976年引入抗儿童开启包装的容器来盛装水杨酸盐和对乙酰氨基酚后，水杨酸盐中毒显著减少。导致幼儿中毒的其他最重要药物有三环类抗抑郁药、苯二氮䓬类药物、洛哌丁胺（地芬诺酯和阿托品）以及铁制剂；根据规定，这些药物也应采用抗儿童开启包装。很少有儿童在接触家用产品中毒后出现症状，但漂白剂、松节油和石蜡也可能采用抗儿童开启包装。在研究期间，故意自我中毒后住院的青春期女孩以及饮酒后住院的青少年男孩人数有所增加。
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