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沙特阿拉伯西部某急诊科就诊患者的药物过量及化学中毒模式

Pattern of drug overdose and chemical poisoning among patients attending an emergency department, western Saudi Arabia.

作者信息

Bakhaidar Mohamad, Jan Saber, Farahat Fayssal, Attar Ahmad, Alsaywid Basim, Abuznadah Wesam

机构信息

Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

出版信息

J Community Health. 2015 Feb;40(1):57-61. doi: 10.1007/s10900-014-9895-x.

Abstract

Poisoning is a medical emergency that represent a major health problem all over the world. Studies on drug overdose and chemical poisoning are very limited in Saudi Arabia (SA). We aimed to describe the current pattern and assess risk factors of drug overdose and chemical poisoning in King Khalid National Guard hospital, Jeddah, SA. Medical records of patients attended emergency department in King Khalid National Guard hospital during the period from January 2008 to December 2012 due to drug overdose and chemical poisoning were reviewed. A total of 129 cases were included in the study. The majority of the population was Saudi (97.7 %), and almost half of them were females (54.3 %). Children under 12 years were the most affected age group (44.2 %). Drug overdose was the most common cause of poisoning (92.2 %). Analgesics and non-steroidal anti-inflammatory drugs represented the highest percentage of used medications (20.4 %). The most commonly reported symptoms were symptoms of the central nervous system (57.4 %) followed by GIT symptoms (41.9 %). Intentional poisoning was reported in 34 cases (26.4 %). Female patients were significantly more likely to attempt suicide than male patients (OR = 7.22, 95 % CI = 1.70, 30.62). Children continue to be at high risk for medication and chemical poisoning. Accessibility to medications at homes encountered for most of poisoning cases among children. Implementing methods to raise public awareness and minimize children access to medications would significantly contribute to reducing burden of this problem on the community.

摘要

中毒是一种医疗急症,是全球范围内的一个重大健康问题。在沙特阿拉伯(SA),关于药物过量和化学中毒的研究非常有限。我们旨在描述沙特吉达市哈立德国民警卫队医院当前药物过量和化学中毒的模式,并评估其风险因素。回顾了2008年1月至2012年12月期间因药物过量和化学中毒到哈立德国民警卫队医院急诊科就诊的患者的病历。该研究共纳入129例病例。大多数患者为沙特人(97.7%),其中近一半为女性(54.3%)。12岁以下儿童是受影响最严重的年龄组(44.2%)。药物过量是中毒最常见的原因(92.2%)。镇痛药和非甾体抗炎药占所用药物的比例最高(20.4%)。最常报告的症状是中枢神经系统症状(57.4%),其次是胃肠道症状(41.9%)。34例(26.4%)报告为故意中毒。女性患者自杀未遂的可能性明显高于男性患者(OR = 7.22,95%CI = 1.70,30.62)。儿童仍然面临药物和化学中毒的高风险。在大多数儿童中毒病例中,家庭中药物容易获取。实施提高公众意识并减少儿童获取药物的方法将显著有助于减轻该问题对社区的负担。

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