Beigh Saba, Mahzari Ali, Alharbi Read A, Al-Ghamdi Rahaf A, Alyahyawi Hanan E, Al-Zahrani Hind A, Al-Jadani Saeedah
Department of Public Health, Faculty of Applied Medical Sciences, Albaha University, Al-Baha 65431, Saudi Arabia.
Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Albaha University, Al-Baha 65431, Saudi Arabia.
Healthcare (Basel). 2023 May 11;11(10):1398. doi: 10.3390/healthcare11101398.
Poisoning is a common and severe problem worldwide. Due to significant growth in the agricultural, chemical, and pharmaceutical industries over the past few decades, poisoning risks have increased with the use of food, chemicals, and medicines everywhere in the world, especially in Saudi Arabia. Advanced information on acute poisoning patterns is critical for the effective management of poisoning events. This study aimed to examine the characteristics of patients with various patterns of acute poisoning, caused by food, drugs, and chemicals, that were reported to the Department of Toxicology and Poison Center at King Fahad Hospital and the Poison Center in Al-Baha Province, Saudi Arabia. The study also examined the relationship between demographic characteristics, including age, toxin type, and geographical distribution, and poisonings in Baha Province. This retrospective cross-sectional analysis included 622 poisoning cases. The data were collected from 2019 to 2022 and it was found that out of 622 instances, 159 had food poisoning, with more men than females sick (53.5% male and 46.5% female), 377 had drug poisoning (54.1% males and 45.9% females), and 86 had chemical poisoning (74.4% males and 25.6% females). This study found that the most prevalent agents implicated in acute poisoning were medicines, particularly analgesics and antipsychotic drugs. Food poisoning was the second most common acute poisoning, affecting largely males followed by female patients. Finally, chemical poisoning involved acute poisoning, with most cases involving methanol and household items including the strongest bleaches (chlorines) (Clorox, Oakland, CA, USA). Insecticides and pesticides were also secondary sources of chemical poisoning. Additional research revealed that the incidence of food, chemical, and drug poisoning was highest in children aged 1-15 years (food poisoning, = 105, 66%; drug poisoning, = 120, 31.8%); patients aged 11-20 years had the highest incidence of chemical poisoning ( = 41, 47.7%). Most poisoning incidents among youngsters are caused by easy access to drugs at home. Implementing strategies to enhance public awareness and limit children's access to drugs would contribute considerably to decreasing the community's burden of this problem. The findings of this study suggest that Al-Baha should improve its education regarding the rational and safe use of drugs and chemicals.
中毒是一个在全球范围内普遍且严重的问题。在过去几十年里,由于农业、化学和制药行业的显著发展,随着食品、化学品和药品在世界各地的广泛使用,中毒风险有所增加,在沙特阿拉伯尤其如此。关于急性中毒模式的先进信息对于有效管理中毒事件至关重要。本研究旨在调查向沙特阿拉伯法赫德国王医院毒理学与中毒中心以及巴哈省中毒中心报告的由食品、药物和化学品引起的各种急性中毒模式患者的特征。该研究还考察了包括年龄、毒素类型和地理分布在内的人口统计学特征与巴哈省中毒情况之间的关系。这项回顾性横断面分析纳入了622例中毒病例。数据收集时间为2019年至2022年,结果发现,在622例病例中,159例为食物中毒,男性患者多于女性患者(男性占53.5%,女性占46.5%);377例为药物中毒(男性占54.1%,女性占45.9%);86例为化学中毒(男性占74.4%,女性占25.6%)。本研究发现,急性中毒中最常见的毒物是药物,尤其是镇痛药和抗精神病药物。食物中毒是第二常见的急性中毒类型,主要影响男性,其次是女性患者。最后,化学中毒涉及急性中毒,大多数病例涉及甲醇和家用物品,包括最强效的漂白剂(含氯清洁剂)(如美国加利福尼亚州奥克兰市的高乐氏漂白剂)。杀虫剂和农药也是化学中毒的次要来源。进一步的研究表明,1至15岁儿童的食品、化学和药物中毒发生率最高(食物中毒,n = 105,占66%;药物中毒,n = 120,占31.8%);11至20岁患者的化学中毒发生率最高(n = 41,占47.7%)。青少年中的大多数中毒事件是由于在家中容易获取药物所致。实施提高公众意识并限制儿童获取药物的策略将极大有助于减轻社区在这一问题上的负担。本研究结果表明,巴哈省应加强关于合理安全使用药物和化学品的教育。