增殖性糖尿病视网膜病变中的抗心磷脂抗体：一个额外的危险因素。
Anticardiolipin antibodies in proliferative diabetic retinopathy: An additional risk factor.
作者信息
Shahin Maha, El-Diasty Amany M, Mabed Mohamed
机构信息
Ophthalmology Department, Faculty of Medicine, Mansoura University, Egypt.
出版信息
Saudi J Ophthalmol. 2009 Jul;23(2):165-9. doi: 10.1016/j.sjopt.2009.06.001. Epub 2009 Aug 5.
PURPOSE
To report the prevalence of anticardiolipin antibodies in patients with proliferative diabetic retinopathy (PDR) having high-risk criteria (HRC).
METHODS
Diabetic patients having PDR with HRC and diabetics free of retinopathy were compared for the presence of anticardiolipin antibodies.
RESULTS
Among the 34 patients, 6 (17.7%) of diabetics having PDR with HRC were positive for anticardiolipin antibodies. There was no significant association of aCL antibodies with sex or type of diabetes. Using Pearson's correlation test, no significant associations of aCL antibodies with duration of diabetes or age of patients were found. All patients who were positive for anticardiolipin antibodies had PDR with HRC. The difference was statistically significant.
CONCLUSION
Presence of anticardiolipin antibodies may represent an additional risk factor for PDR.
目的
报告具有高危标准（HRC）的增殖性糖尿病视网膜病变（PDR）患者中抗心磷脂抗体的患病率。
方法
比较患有PDR且具有HRC的糖尿病患者和无视网膜病变的糖尿病患者中抗心磷脂抗体的存在情况。
结果
在34例患者中，6例（17.7%）患有PDR且具有HRC的糖尿病患者抗心磷脂抗体呈阳性。抗心磷脂抗体与性别或糖尿病类型无显著关联。使用Pearson相关性检验，未发现抗心磷脂抗体与糖尿病病程或患者年龄有显著关联。所有抗心磷脂抗体呈阳性的患者均患有PDR且具有HRC。差异具有统计学意义。
结论
抗心磷脂抗体的存在可能是PDR的另一个危险因素。
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