Al-Akily Saleh A, Bamashmus Mahfouth A
Department of Ophthalmology, Faculty of Medicine and Health Sciences, Sana'a University, Yemen ; Ibn Al-Haitham Eye Center, University of Science and Technology, Sana'a, Yemen.
Saudi J Ophthalmol. 2011 Jul;25(3):291-4. doi: 10.1016/j.sjopt.2011.02.001. Epub 2011 Feb 16.
The objective of this study was to assess the ocular complications and visual loss among patients with severe vernal keratoconjunctivitis (VKC).
Four hundred and thirty-one patients with VKC seen at Ibn Al-Haitham Eye Center were the study group. This is a retrospective non-comparative observational study between 01 January 2002 and 31 December 2002. Visual acuity was measured with the standard Snellen visual acuity chart and for children under 5 years of age Kay pictures were used. Visual impairment was assessed by means of the World Health Organization criteria for visual disabilities. Cases with severe VKC that developed ocular complications leading to blindness and severe visual impairment were analyzed.
The majority of VKC patients were males (75.9%) with a male:female ratio of 3.1:1. A total of 68 (15.7%) patients (54 boys and 14 girls) had severe VKC. The ocular findings among 20 patients with severe VKC that led to blindness and severe visual impairment included keratoconus (7); steroid-induced cataract (5), central corneal scars (5) and steroid-induced glaucoma (3). Two of the keratoconus cases developed acute hydrops.
Severe VKC in developing countries including Yemen is a potentially blinding disease. Visual loss may be due to keratoconus and corneal scars, as well as complications of the unsupervised use of topically administered corticosteroids.
本研究的目的是评估重度春季角结膜炎（VKC）患者的眼部并发症及视力丧失情况。
在伊本·海赛姆眼科中心就诊的431例VKC患者作为研究组。这是一项2002年1月1日至2002年12月31日期间的回顾性非对照观察性研究。使用标准的斯内伦视力表测量视力，5岁以下儿童使用凯氏图片。采用世界卫生组织视力残疾标准评估视力损害情况。对发生导致失明和严重视力损害的眼部并发症的重度VKC病例进行分析。
大多数VKC患者为男性（75.9%），男女比例为3.1:1。共有68例（15.7%）患者（54名男孩和14名女孩）患有重度VKC。20例导致失明和严重视力损害的重度VKC患者的眼部检查结果包括圆锥角膜（7例）；类固醇性白内障（5例）、中央角膜瘢痕（5例）和类固醇性青光眼（3例）。其中2例圆锥角膜病例发生了急性角膜水肿。
在包括也门在内的发展中国家，重度VKC是一种潜在的致盲性疾病。视力丧失可能是由于圆锥角膜和角膜瘢痕，以及局部使用皮质类固醇药物监管不当所致的并发症。
