*Department of Orthopaedics, University of Utah, Salt Lake City, UT †Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada ‡Department of Neurosurgery, Rush University, Chicago, IL §Department of Orthopaedic Surgery, Emory University, Atlanta, GA ¶Department of Orthopaedic Surgery, Harborview Medical Center, University of Washington, Seattle, WA; and ‖Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.
Spine (Phila Pa 1976). 2013 Oct 15;38(22 Suppl 1):S171-2. doi: 10.1097/BRS.0b013e3182a7f4ff.
Degenerative cervical myelopathy (DCM), including cervical spondylotic myelopathy and ossification of the posterior longitudinal ligament, presents a heterogeneous set of variables reflecting its complex nature. Multiple studies in the past have attempted to elucidate an ideal surgical algorithm that surgeons may use when treating these patients, unfortunately all studies to date, including the rigorous systematic review used in this focus issue, have fallen short in identifying a superior approach when addressing DCM. Likely because of a superior approach being nonexistent because there are multiple pathoanatomical considerations. In addition to the multitude of variables that spine surgeons face when deciding the treatment options for patients with DCM, the previous studies that have been published, unfortunately, lack in consistent outcome and complication reporting. Therefore, synthesizing a treatment algorithm remains difficult, however, the articles in this focus issue use the GRADE system to assess the overall quality (strength) of available evidence and, where appropriate, formulate evidence-based recommendations. Factors that should be included in surgical decision making are the sagittal alignment, anatomical location of the compressive pathology, number of levels of compression, presence of absence or instability or subluxation, the type compressive pathology (e.g., spondylosis vs. ossification of the posterior longitudinal ligament), neck anatomy, bone quality, and surgeon experience or preference. Fortunately, as reviewed in the accompanying articles, a number of excellent surgical options exist that can be selected on the basis of the aforementioned pathoanatomical considerations.
退行性颈椎脊髓病(DCM)包括颈椎病和后纵韧带骨化,表现出一组反映其复杂性的异质变量。过去的多项研究试图阐明一种理想的手术算法,以便外科医生在治疗这些患者时使用,但迄今为止所有的研究,包括本专题中使用的严格系统评价,在确定治疗 DCM 的优势方法方面都失败了。可能是因为因为存在多种病理解剖学考虑因素,所以不存在优势方法。除了脊柱外科医生在为 DCM 患者决定治疗方案时面临的众多变量外,不幸的是,以前发表的研究在结果和并发症报告方面缺乏一致性。因此,综合治疗算法仍然很困难,然而,本专题中的文章使用 GRADE 系统评估现有证据的总体质量(强度),并在适当的情况下制定基于证据的建议。手术决策中应包括矢状位排列、压迫性病变的解剖位置、受压水平的数量、是否存在不稳定或半脱位、压迫性病变的类型(例如,颈椎病与后纵韧带骨化)、颈部解剖结构、骨质量以及外科医生的经验或偏好。幸运的是,正如随附文章中所回顾的那样,存在许多可以根据上述病理解剖学考虑因素选择的出色手术选择。