Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China
BMJ Open. 2024 Oct 23;14(10):e085050. doi: 10.1136/bmjopen-2024-085050.
Axial symptoms (AS) represent one of the primary complications after cervical spondylotic myelopathy (CSM) surgery. Traditional Chinese Medicine (TCM), as a complementary and alternative therapy, is widely used in the treatment of postoperative AS in CSM. However, it lacks standardised treatment protocols, uniform therapeutic criteria, assessment methods and a sufficiently in-depth understanding of its mechanisms of action. These shortcomings impact the credibility of TCM treatment in clinical practice.
We will conduct comprehensive searches, both manual and electronic, on literature published up to 31 July 2024, and database searches will commence after the publication of this agreement, with an estimated commencement date of 1 October 2024 and the end date of 31 March 2025, without language restrictions. Key databases such as MEDLINE, PubMed, Embase, Web of Science, Cochrane Library, WHO International Clinical Trial Registration Platform, China National Knowledge Network, China Biomedical Literature Database, China Scientific Journal Database and Wanfang Database will be explored. In addition, we will include resources such as library journals and conference abstracts. After identifying and screening all randomised controlled trials focused on TCM for postoperative AS of CSM, the two investigators will conduct a meta-analysis of the included studies. The results will be summarised as the risk ratio for binary data and the standardised or weighted average difference for continuous data.
Ethical approval is not required since this review does not involve individual patient data. The review's findings will provide clinicians with evidence on using TCM treatment for AS post-CSM surgery, disseminated through peer-reviewed publications or conferences.
CRD42024505160.
轴性症状（AS）是颈椎脊髓病（CSM）手术后的主要并发症之一。作为一种补充和替代疗法，中药（TCM）广泛应用于 CSM 术后 AS 的治疗。然而，它缺乏标准化的治疗方案、统一的治疗标准、评估方法以及对其作用机制的充分深入了解。这些缺陷影响了 TCM 在临床实践中的治疗可信度。
我们将对截至 2024 年 7 月 31 日发表的文献进行全面的检索，包括手动检索和电子检索，并在本协议发布后开始数据库检索，预计开始日期为 2024 年 10 月 1 日，结束日期为 2025 年 3 月 31 日，不限制语言。将探索 MEDLINE、PubMed、Embase、Web of Science、Cochrane 图书馆、世界卫生组织国际临床试验注册平台、中国国家知识网络、中国生物医学文献数据库、中国科学期刊数据库和万方数据库等关键数据库。此外，我们还将包括图书馆期刊和会议摘要等资源。在确定并筛选所有针对 CSM 术后 AS 的 TCM 的随机对照试验后，两名调查员将对纳入的研究进行荟萃分析。结果将以二分类数据的风险比和连续数据的标准化或加权均数差进行总结。
由于本综述不涉及个体患者数据，因此不需要伦理批准。该综述的结果将为临床医生提供使用 TCM 治疗 CSM 术后 AS 的证据，并通过同行评议的出版物或会议进行传播。
CRD42024505160。
