Department of Radiology, Wakayama Medical University, Wakayama 641-8510, Japan.
World J Gastroenterol. 2013 Aug 21;19(31):5125-30. doi: 10.3748/wjg.v19.i31.5125.
To evaluate the effectiveness and safety of emergency balloon-occluded retrograde transvenous obliteration (BRTO) for ruptured gastric varices.
Emergency BRTO was performed in 17 patients with gastric varices and gastrorenal or gastrocaval shunts within 24 h of hematemesis and/or tarry stool. The gastric varices were confirmed by endoscopy, and the gastrorenal or gastrocaval shunts were identified by contrast-enhanced computed tomography (CE-CT). A 6-Fr balloon catheter (Cobra type) was inserted into the gastrorenal shunt via the right internal jugular vein, or into the gastrocaval shunt via the right femoral vein, depending on the varices drainage route. The sclerosant, 5% ethanolamine oleate iopamidol, was injected into the gastric varices through the catheter during balloon occlusion. In patients with incomplete thrombosis of the varices after the first BRTO, a second BRTO was performed the following day. Patients were followed up by endoscopy and CE-CT at 1 d, 1 wk, and 1, 3 and 6 mo after the procedure, and every 6 mo thereafter.
Complete thrombosis of the gastric varices was not achieved with the first BRTO in 7/17 patients because of large gastric varices. These patients underwent a second BRTO on the next day, and additional sclerosant was injected through the catheter. Complete thrombosis which led to disappearance of the varices was achieved in 16/17 patients, while the remaining patient had incomplete thrombosis of the varices. None of the patients experienced rebleeding or recurrence of the gastric varices after a median follow-up of 1130 d (range 8-2739 d). No major complications occurred after the procedure. However, esophageal varices worsened in 5/17 patients after a mean follow-up of 8.6 mo.
Emergency BRTO is an effective and safe treatment for ruptured gastric varices.
评估急诊球囊阻塞逆行经静脉闭塞术(BRTO)治疗破裂性胃静脉曲张的有效性和安全性。
对 17 例呕血和/或柏油样便的胃静脉曲张并伴有胃肾或胃腔静脉分流的患者,在出血后 24 小时内进行急诊 BRTO。胃静脉曲张通过内镜检查证实,胃肾或胃腔静脉分流通过增强 CT(CE-CT)确定。通过右颈内静脉将 6Fr 球囊导管(Cobra 型)插入胃肾分流,或通过右股静脉将其插入胃腔静脉分流,具体取决于静脉曲张引流途径。在球囊闭塞期间,通过导管将硬化剂 5%乙醇胺油酸异帕米醇注入胃静脉曲张。在第一次 BRTO 后,对 7/17 例患者中静脉曲张不完全闭塞的患者进行了第二次 BRTO。在手术后 1d、1wk、1、3 和 6mo 以及此后每 6mo 进行内镜和 CE-CT 随访。
由于胃静脉曲张较大,17 例患者中有 7 例在第一次 BRTO 中未实现胃静脉曲张完全闭塞。这些患者在第二天进行了第二次 BRTO,并通过导管注入额外的硬化剂。16/17 例患者实现了完全闭塞,导致静脉曲张消失,而其余 1 例患者的静脉曲张仍未完全闭塞。17 例患者在中位随访 1130d(8-2739d)后均未再发生出血或胃静脉曲张复发。在操作后,未发生任何主要并发症。然而,在平均随访 8.6mo 后,5/17 例患者的食管静脉曲张恶化。
急诊 BRTO 是治疗破裂性胃静脉曲张的一种有效且安全的治疗方法。