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氯吡格雷致 ST 段抬高型心肌梗死患者发生肺出血

Pulmonary Alveolar Hemorrhage after Clopidogrel Use for ST Elevation Myocardial Infarction.

机构信息

Division of Cardiology, Department of Internal Medicine, Konkuk University College of Medicine, Chungju, Korea.

出版信息

Korean Circ J. 2013 Jul;43(7):497-9. doi: 10.4070/kcj.2013.43.7.497. Epub 2013 Jul 31.

Abstract

Combination treatment of antiplatelet drugs containing aspirin and clopidogrel reduces systemic ischemic events after percutaneous coronary intervention (PCI) in high risk patients. However, this combination treatment of antiplatelet drugs is associated with increased risk of nonfatal and fatal bleeding. Diffuse alveolar hemorrhage after PCI is a rare complication that has been mostly reported in association with glycoprotein IIb/IIIa inhibitors. We report the case of a 62-year-old man who presented with ST elevation myocardial infarction and suffered a diffuse alveolar hemorrhage after clopidogrel use following primary PCI.

摘要

双联抗血小板治疗(包含阿司匹林和氯吡格雷)可降低高危经皮冠状动脉介入治疗(PCI)患者的系统性缺血事件。然而,这种双联抗血小板药物治疗与非致死性和致死性出血风险增加相关。PCI 后弥漫性肺泡出血是一种罕见的并发症,主要与糖蛋白 IIb/IIIa 抑制剂相关。我们报告了一例 62 岁男性患者,因 ST 段抬高型心肌梗死就诊,在初次 PCI 后使用氯吡格雷后发生弥漫性肺泡出血。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91fd/3744739/571b7d0f0eef/kcj-43-497-g001.jpg

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