Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Center for Infectious Research (HZI), Saarbrücken, Germany.
J Biotechnol. 2013 Oct 10;168(1):117-8. doi: 10.1016/j.jbiotec.2013.08.013. Epub 2013 Aug 18.
The complete genome sequence of Streptomyces fulvissimus (DSM 40593), consisting of a linear chromosome with a size of 7.9Mbp, is reported. Preliminary data indicates that the chromosome of S. fulvissimus contains 32 putative gene clusters involved in the biosynthesis of secondary metabolites, two of them showing very high similarity to the valinomycin and nonactin biosynthetic clusters. The availability of genome sequence of S. fulvissimus will contribute to the evaluation of the full biosynthetical potential of streptomycetes.
报道了黄色链霉菌（DSM 40593）的完整基因组序列，该序列由一条大小为 7.9Mbp 的线性染色体组成。初步数据表明，黄色链霉菌的染色体包含 32 个可能参与次生代谢物生物合成的基因簇，其中两个与缬氨霉素和尼奥他汀生物合成簇具有非常高的相似性。黄色链霉菌基因组序列的可用性将有助于评估链霉菌的全生物合成潜力。
