儿童系统性红斑狼疮中的低补体水平与菌血症风险
Low complement levels in paediatric systemic lupus erythematosus and the risk of bacteraemia.
作者信息
Hagen Jaap P, Muller Petra C E Hissink, Bredius Robbert G M, ten Cate Rebecca
机构信息
Department of Paediatrics, Leiden University Medical Centre, Leiden, The Netherlands.
出版信息
BMJ Case Rep. 2013 Aug 21;2013:bcr2013010378. doi: 10.1136/bcr-2013-010378.
Abstract
This report describes an 11-year-old girl with systemic lupus erythematosus (SLE) with long-standing low levels of complement proteins. A disease period with lupus nephritis (class IIIa) was complicated by Staphylococcus aureus bacteraemia and osteomyelitis. She was treated with high-dose immunosuppressants and 6 weeks of high-dose intravenous antibiotics. The clinician should be aware of bacteraemia in SLE with secondary complement deficiency.
摘要
本报告描述了一名11岁患有系统性红斑狼疮（SLE）且长期补体蛋白水平低下的女孩。一段狼疮性肾炎（IIIa级）病程并发了金黄色葡萄球菌菌血症和骨髓炎。她接受了大剂量免疫抑制剂治疗以及为期6周的大剂量静脉抗生素治疗。临床医生应注意继发补体缺乏的SLE患者发生菌血症的情况。
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