尼日利亚消化不良患者的幽门螺杆菌感染
Helicobacter pylori infection in Nigerians with dyspepsia.
作者信息
Olokoba A B, Gashau W, Bwala S, Adamu A, Salawu F K
机构信息
Department Of Medicine, University Of Ilorin, Ilorin, Kwara 240001, Nigeria.
出版信息
Ghana Med J. 2013 Jun;47(2):79-81.
BACKGROUND
Helicobacter pylori is the most common chronic bacterial infection, and a significant aetiological factor in acid peptic diseases and gastric cancer. Dyspepsia is a common gastrointestinal disorder, and the most common indication for gastroscopy. Detection of this organism during endoscopy has become standard clinical practice. We determine the prevalence of H. pylori infection among dyspeptic patients using serology and histology.
METHODS
Patients with dyspepsia underwent gastroscopy, and biopsies were taken from the antral portions of their stomach and processed. Their serum samples were tested for H. pylori infection using ELISA to detect anti-bodies.
RESULTS
One hundred and twenty-five patients, comprising 49 (39.2%) males and 76 (60.8%) females were studied. A prevalence rate of 93.6% for H. pylori was found by serology while a rate of 80.0% was found by histology.
CONCLUSION
There is a high prevalence of H. pylori infection in patients with dyspepsia; and a high percentage of detection by serological and histological tests.
背景
幽门螺杆菌是最常见的慢性细菌感染，是酸相关性疾病和胃癌的重要病因。消化不良是常见的胃肠道疾病，也是胃镜检查最常见的适应证。在内镜检查期间检测该病原体已成为标准临床实践。我们使用血清学和组织学方法确定消化不良患者中幽门螺杆菌感染的患病率。
方法
消化不良患者接受胃镜检查，并从胃窦部取活检组织进行处理。使用酶联免疫吸附测定法（ELISA）检测其血清样本中的幽门螺杆菌感染情况以检测抗体。
结果
共研究了125例患者，其中男性49例（39.2%），女性76例（60.8%）。血清学检测幽门螺杆菌感染率为93.6%，组织学检测率为80.0%。
结论
消化不良患者中幽门螺杆菌感染率很高；血清学和组织学检测的检出率很高。
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