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1例在双侧颈动脉狭窄(烟雾病)病程中诊断出的格雷夫斯病;病例报告及文献复习

A case of graves' disease diagnosed in the course of bilateral carotid artery stenoses (moyamoya disease); a case report and review of the literature.

作者信息

Kamasaki Hotaka, Takeuchi Takako, Mikami Takeshi, Komeichi Katsuhide, Tsutsumi Hiroyuki

机构信息

Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo, Japan.

出版信息

Clin Pediatr Endocrinol. 2013 Jul;22(3):39-44. doi: 10.1292/cpe.22.39. Epub 2013 Aug 1.

Abstract

A 14-year-old boy was admitted to our hospital after being diagnosed at a local clinic with bilateral carotid artery stenoses (Moyamoya disease) and mild thyrotoxicosis. A blood examination showed suppressed TSH and elevated triiodothyronine and thyroxine levels; however, he was negative for anti-thyrotropin receptor antibody (TRAB) and thyroid stimulating antibody (TSAB). Concern about a possible thyroid crisis led us to administer thiamazole (MMI) and potassium iodide (KI), following which encephalo-duro-arterio-synangiosis (EDAS) of the left side was performed successfully. After about 1 mo, he became positive for TRAB and TSAB. He was thought to have Graves' disease and Moyamoya disease coincidentally. Several factors are considered to be involved in the coincidental onset of these two diseases.

摘要

一名14岁男孩在当地诊所被诊断为双侧颈动脉狭窄(烟雾病)和轻度甲状腺毒症后入住我院。血液检查显示促甲状腺激素(TSH)降低,三碘甲状腺原氨酸和甲状腺素水平升高;然而,他的抗促甲状腺激素受体抗体(TRAB)和甲状腺刺激抗体(TSAB)呈阴性。由于担心可能发生甲状腺危象,我们给他使用了甲巯咪唑(MMI)和碘化钾(KI),随后成功进行了左侧脑硬膜动脉血管融合术(EDAS)。大约1个月后,他的TRAB和TSAB呈阳性。他被认为同时患有格雷夫斯病和烟雾病。这两种疾病的同时发病被认为涉及几个因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/715c/3748282/c4c0bb59b61e/cpe-22-039-g001.jpg

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