降钙素原作为决定是否干预尿路感染的有用标志物。
Procalcitonin as a useful marker to decide upon intervention for urinary tract infection.
机构信息
Department of Urology, Kinki University Faculty of Medicine, Osaka-Sayama, Japan ; Department of Urology, Sakai Hospital, Kinki University Faculty of Medicine, Sakai, Osaka, Japan.
出版信息
Infect Drug Resist. 2013 Aug 7;6:83-6. doi: 10.2147/IDR.S47161. eCollection 2013.
BACKGROUND
Because the use of procalcitonin has been advocated as a marker of bacterial infection, this study was carried out to determine the usefulness of serum PCT as an early marker to decide upon intervention for urinary tract infection.
METHODS
The subjects were 68 patients with urinary tract infection (UTI) in whom we measured serum procalcitonin concentration at the start of treatment.
RESULTS
There were 47 patients with nonobstructed UTI and 21 with obstructed UTI. All patients with obstructed UTI were subjected to intervention. There were significant differences in procalcitonin, white blood cells, and creatinine levels between patients with nonobstructed and obstructed UTI (P < 0.05).
CONCLUSION
Although this retrospective study comprised a small number of patients, we found that procalcitonin was a useful marker to decide upon urinary intervention.
背景
由于降钙素原的使用被提倡作为细菌感染的标志物，本研究旨在确定血清 PCT 作为早期标志物来决定是否干预尿路感染的有用性。
方法
本研究的对象是 68 例尿路感染（UTI）患者，我们在治疗开始时测量了他们的血清降钙素原浓度。
结果
47 例患者为非梗阻性 UTI，21 例患者为梗阻性 UTI。所有梗阻性 UTI 患者均接受了干预。非梗阻性和梗阻性 UTI 患者的降钙素原、白细胞和肌酐水平有显著差异（P < 0.05）。
结论
尽管这是一项回顾性研究，纳入的患者数量较少，但我们发现降钙素原是决定是否进行尿路干预的有用标志物。
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