Staten Island University Hospital, Staten Island, NY, USA.
Int J Gen Med. 2013 Aug 9;6:665-9. doi: 10.2147/IJGM.S47397. eCollection 2013.
Calciphylaxis is a challenging complication of end-stage renal disease, with an unknown underlying mechanism. Several risk factors have been identified, such as hyperphosphatemia, hypercalcemia, hyperparathyroidism, low serum albumin levels, and history of warfarin therapy. This article presents a case of calciphylaxis provoked by reintroduction of warfarin therapy, introducing the possibility of direct induction.
钙化防御是终末期肾病的一种具有挑战性的并发症,其潜在机制尚不清楚。已经确定了几个危险因素,如高磷血症、高钙血症、甲状旁腺功能亢进症、低血清白蛋白水平和华法林治疗史。本文介绍了一例因重新开始华法林治疗而引发的钙化防御病例,提出了直接诱导的可能性。