Scaramuzzo Rosa T, Ciantelli Massimiliano, Baldoli Ilaria, Bellanti Lisa, Gentile Marzia, Cecchi Francesca, Sigali Emilio, Tognarelli Selene, Ghirri Paolo, Mazzoleni Stefano, Menciassi Arianna, Cuttano Armando, Boldrini Antonio, Laschi Cecilia, Dario Paolo
Centro di Formazione e Simulazione Neonatale "NINA," UO Neonatologia, Azienda Ospedaliera Universitaria Pisana, Pisa, Italy ; Istituto di Scienze della Vita, Italy.
Med Devices (Auckl). 2013 Aug 8;6:115-21. doi: 10.2147/MDER.S45524. eCollection 2013.
Respiratory function is mandatory for extrauterine life, but is sometimes impaired in newborns due to prematurity, congenital malformations, or acquired pathologies. Mechanical ventilation is standard care, but long-term complications, such as bronchopulmonary dysplasia, are still largely reported. Therefore, continuous medical education is mandatory to correctly manage devices for assistance. Commercially available breathing function simulators are rarely suitable for the anatomical and physiological realities. The aim of this study is to develop a high-fidelity mechatronic simulator of neonatal airways and lungs for staff training and mechanical ventilator testing. The project is divided into three different phases: (1) a review study on respiratory physiology and pathophysiology and on already available single and multi-compartment models; (2) the prototyping phase; and (3) the on-field system validation.
呼吸功能是宫外生存所必需的，但由于早产、先天性畸形或后天性疾病，新生儿的呼吸功能有时会受损。机械通气是标准治疗方法，但诸如支气管肺发育不良等长期并发症仍有大量报道。因此，持续医学教育对于正确管理辅助设备是必不可少的。市售的呼吸功能模拟器很少适用于解剖学和生理学实际情况。本研究的目的是开发一种用于员工培训和机械通气测试的高保真新生儿气道和肺部机电模拟器。该项目分为三个不同阶段：(1) 对呼吸生理学和病理生理学以及现有的单室和多室模型进行综述研究；(2) 原型制作阶段；(3) 现场系统验证。
