Liu Changjiang, Li Hui, Yang Kedi, Yang Haixia
School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, P.R. China.
Iran J Public Health. 2013 Jun 1;42(6):639-42. eCollection 2013.
Melamine is a new risk of urinary stones. Gansu province is a heavily affected area and has large population and underdeveloped economy. We hypothesized that number of family members and family income may play significant roles in the formation of urinary stones. A case-control study was performed among 190 infants. Results showed that the case group had less numbers of family members than the control (4.4 vs. 5.6, respectively). The multivariate logistic regression analysis indicated that number of family members was an independent influencing factor associated with urinary stones (OR, 0.606; 95% CI, 0.411-0.893; P = 0.011). Family income, however, did not exhibit a significant difference. Observed results suggested that number of family members was a new and significant influencing factor to affect the risk of melamine-associated urinary stones.
三聚氰胺是尿路结石的一种新风险因素。甘肃省是受影响严重的地区，人口众多且经济欠发达。我们推测家庭成员数量和家庭收入可能在尿路结石的形成中发挥重要作用。对190名婴儿进行了一项病例对照研究。结果显示，病例组的家庭成员数量少于对照组（分别为4.4人和5.6人）。多因素逻辑回归分析表明，家庭成员数量是与尿路结石相关的独立影响因素（比值比，0.606；95%可信区间，0.411 - 0.893；P = 0.011）。然而，家庭收入并未表现出显著差异。观察结果表明，家庭成员数量是影响三聚氰胺相关尿路结石风险的一个新的重要影响因素。
