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加纳一家三级医院中由高血压疾病导致的孕产妇死亡。

Maternal deaths attributable to hypertensive disorders in a tertiary hospital in Ghana.

机构信息

Department of Obstetrics and Gynecology, Korle Bu Teaching Hospital, Accra, Ghana.

出版信息

Int J Gynaecol Obstet. 2013 Nov;123(2):110-3. doi: 10.1016/j.ijgo.2013.05.017. Epub 2013 Aug 1.

Abstract

OBJECTIVE

To determine the contribution of hypertensive disorders of pregnancy to maternal deaths at Korle Bu Teaching Hospital (KBTH) in Accra, Ghana.

METHODS

The retrospective descriptive study conducted at KBTH during 2010-2011 involved a comprehensive review of all maternal deaths attributable to hypertensive disorders.

RESULTS

There were 21 385 deliveries, 21742 live births, and 199 maternal deaths, resulting in a maternal mortality ratio of 915.3 per 100000 live births. In total, 63 (31.7%) maternal deaths were attributable to hypertensive disorders with a case fatality rate of 3.9%. The incidence of hypertensive disorders of pregnancy was 7.6%. Hypertensive disorders were the most common direct cause of maternal death followed by obstetric hemorrhage (26.6%), unsafe abortion (11.1%), and puerperal sepsis (3.5%). Most (38.1%) hypertension-related maternal deaths occurred within 24hours of admission and the majority (79.4%) had been referred. Eclampsia was the leading immediate cause of hypertension-related death (23.8%), followed by acute renal failure (20.6%), intracerebral hemorrhage (15.9%), and pulmonary edema (12.7%).

CONCLUSION

Hypertensive diseases are the leading cause of maternal death at KBTH, having overtaken obstetric hemorrhage, with eclampsia, acute renal failure, intracerebral hemorrhage, and pulmonary edema representing the major immediate causes of hypertension-related maternal death.

摘要

目的

确定在加纳阿克拉的科勒布教学医院(KBTH),妊娠高血压疾病对产妇死亡的影响。

方法

这项 2010-2011 年在 KBTH 进行的回顾性描述性研究,全面审查了所有归因于高血压疾病的产妇死亡病例。

结果

共有 21385 次分娩,21742 例活产和 199 例产妇死亡,导致每 100000 例活产的产妇死亡率为 915.3。总共有 63 例(31.7%)产妇死亡归因于高血压疾病,病死率为 3.9%。妊娠高血压疾病的发病率为 7.6%。高血压疾病是导致产妇死亡的最常见直接原因,其次是产科出血(26.6%)、不安全流产(11.1%)和产褥期脓毒症(3.5%)。大多数(38.1%)与高血压相关的产妇死亡发生在入院后 24 小时内,且大多数(79.4%)患者是被转来的。子痫是与高血压相关死亡的主要直接原因(23.8%),其次是急性肾衰竭(20.6%)、脑出血(15.9%)和肺水肿(12.7%)。

结论

在 KBTH,高血压疾病是产妇死亡的主要原因,已超过产科出血,子痫、急性肾衰竭、脑出血和肺水肿是与高血压相关的产妇死亡的主要直接原因。

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