一项基于行业的队列研究，探讨了轮班工人体重增加与高血压风险之间的关系。
An industry-based cohort study of the association between weight gain and hypertension risk among rotating shift workers.
机构信息
Department of Public Health, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
出版信息
J Occup Environ Med. 2013 Sep;55(9):1041-5. doi: 10.1097/JOM.0b013e31829731fd.
OBJECTIVES
We investigated whether the association between shift work and hypertension is independent of weight gain.
METHODS
Subjects were 10,173 male employees (9209 daytime workers, 964 three-shift workers; mean follow-up period: 12.7 years). Hypertension was defined as systolic blood pressure 140 mm Hg or more or diastolic blood pressure 90 mm Hg or more. The risk of developing hypertension among shift workers was estimated using a Cox proportional hazards model with adjustment for several factors.
RESULTS
Analysis revealed that "shift work" (hazard ratio [HR]: 1.85; 95% confidence interval [CI]: 1.68, 2.03), "baseline body mass index" (HR: 1.13; 95% CI: 1.12, 1.15), and "increase in body mass index during follow-up" (HR: 1.15; 95% CI: 1.13, 1.17) were significant independent risk factors for hypertension.
CONCLUSIONS
Shift work is a significant risk factor for hypertension that is independent of both starting weight and weight gained over years of work.
目的
我们旨在研究轮班工作与高血压之间的关联是否独立于体重增加。
方法
本研究的对象为 10173 名男性员工（9209 名白班工人，964 名三班倒工人；平均随访时间：12.7 年）。高血压的定义为收缩压 140mmHg 或以上，或舒张压 90mmHg 或以上。采用 Cox 比例风险模型，调整了多种因素后，对轮班工人发生高血压的风险进行了估计。
结果
分析表明，“轮班工作”（风险比 [HR]：1.85；95%置信区间 [CI]：1.68，2.03）、“基线体重指数”（HR：1.13；95%CI：1.12，1.15）和“随访期间体重指数的增加”（HR：1.15；95%CI：1.13，1.17）是高血压的显著独立危险因素。
结论
轮班工作是高血压的一个重要危险因素，与起始体重和多年工作期间体重增加均无关。
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