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通过16s核糖体RNA测序确诊的缺陷乏养菌泡相关性眼内炎

Abiotrophia defectiva bleb-associated endophthalmitis confirmed with 16s ribosomal RNA sequencing.

作者信息

Hugo Lee Ming-Han, Lawlor Mitchell, Lee Anne J

机构信息

*University of New South Wales †Department of Ophthalmology, Liverpool Hospital, Liverpool §Glaucoma Unit, Sydney Eye Hospital, Sydney, NSW, Australia ‡Moorfields Eye Hospital, London, UK.

出版信息

J Glaucoma. 2015 Jan;24(1):87-8. doi: 10.1097/IJG.0b013e3182953ad9.

Abstract

One recognized complication of trabeculectomy with visually devastating potential is blebitis. We present a case of a 74-year-old woman with a culture and polymerase chain reaction-positive Abiotrophia defectiva bleb-associated endophthalmitis. Abiotrophia defectiva is a rare but possible cause of endophthalmitis secondary to blebitis and should be considered in culture-negative cases. Prompt identification, hence directed eradication, of the causative organism in such visually threatening cases may be facilitated by requesting polymerase chain reaction and 16S ribosomal RNA sequencing.

摘要

小梁切除术一种公认的具有视力严重受损风险的并发症是滤过泡炎。我们报告一例74岁女性患者,其滤过泡相关眼内炎经培养及聚合酶链反应检测证实为缺陷嗜养菌阳性。缺陷嗜养菌是滤过泡炎继发眼内炎的一种罕见但可能的病因,在培养结果为阴性的病例中应予以考虑。对于此类有视力威胁的病例,通过进行聚合酶链反应和16S核糖体RNA测序,有助于及时识别并进而根除致病微生物。

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