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用于记录人呼吸道上皮细胞跨上皮离子转运的有机电化学晶体管阵列。

Organic electrochemical transistor array for recording transepithelial ion transport of human airway epithelial cells.

机构信息

Bioengineering Graduate Program, Division of Biomedical Engineering, The Hong Kong University of Science and Technology, Hong Kong, China.

出版信息

Adv Mater. 2013 Dec 3;25(45):6575-80. doi: 10.1002/adma.201302615. Epub 2013 Aug 23.

Abstract

An organic electrochemical transistor array is integrated with human airway epithelial cells. This integration provides a novel method to couple transepithelial ion transport with electrical current. Activation and inhibition of transepithelial ion transport are readily detected with excellent time resolution. The organic electrochemical transistor array serves as a promising platform for physiological studies and drug testing.

摘要

有机电化学晶体管阵列与人呼吸道上皮细胞集成。这种集成提供了一种将跨上皮离子转运与电流相耦合的新方法。跨上皮离子转运的激活和抑制可以很容易地以优异的时间分辨率进行检测。有机电化学晶体管阵列为生理研究和药物测试提供了一个有前途的平台。

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