Department of Health Statistics, School of Public Health, Shanxi Medical University, People's Republic of China.
J Geriatr Psychiatry Neurol. 2013 Dec;26(4):230-6. doi: 10.1177/0891988713500586. Epub 2013 Aug 22.
To evaluate the psychometric properties of the quality of life-Alzheimer disease (QOL-AD) Chinese version in patients with dementia in mainland, China and to compare patient and caregiver reports of patient QOL.
The QOL-AD Chinese version was established following standard guidelines for cross-cultural adaptation of measures. The reliability was assessed by internal consistency and test-retest reliability. The validity included construct and convergent validity. A paired Student t test was performed to determine differences between patient reports and caregiver reports.
The reliability for both patient and caregiver reports on the QOL-AD was good (Cronbach α values of 0.66 and 0.87; intraclass correlation coefficients of 0.84 and 0.90 for patient and caregiver reports, respectively). The validity of patient and caregiver reports was supported by correlation with domain measures. All of the multitrait-multimethod correlations demonstrated a high relationship between patient reports and caregiver reports, ranging from 0.26 to 0.55. The caregivers rated patient QOL significantly higher than did the patients.
The findings support the use of the Chinese version of the QOL-AD as a generic instrument to measure QOL of AD in mainland China. Further research is needed to clarify the relationship between patient and caregiver reports of patient QOL.
评估适用于中国大陆痴呆患者的生活质量-阿尔茨海默病量表（QOL-AD）中文版的心理测量特性，并比较患者和照护者报告的患者生活质量。
QOL-AD 中文版是按照跨文化测量的标准指南建立的。通过内部一致性和重测信度评估可靠性。有效性包括结构和收敛效度。采用配对学生 t 检验来确定患者报告和照护者报告之间的差异。
患者和照护者报告的 QOL-AD 的可靠性均良好（患者和照护者报告的 Cronbach α 值分别为 0.66 和 0.87；患者和照护者报告的组内相关系数分别为 0.84 和 0.90）。患者和照护者报告的有效性得到了与领域测量的相关性的支持。所有多特质-多方法相关性均表明患者报告和照护者报告之间存在高度相关性，范围为 0.26 至 0.55。照护者对患者生活质量的评价明显高于患者。
研究结果支持使用 QOL-AD 中文版作为一种通用工具来衡量中国大陆 AD 患者的生活质量。需要进一步研究来阐明患者和照护者报告的患者生活质量之间的关系。
