[口腔癌肉瘤的极速进展]
[Extremely rapid progression of oral cavity carcinosarcoma].
作者信息
Lebourg G, de Muret A, Goga D
机构信息
Service de chirurgie maxillo-faciale et stomatologie, CHU de Tours, avenue de la République, 37170 Chambray-lès-Tours, France.
Service d'anatomo-pathologie et cytologie, CHU de Tours, avenue de la République, 37170 Chambray-lès-Tours, France.
出版信息
Rev Stomatol Chir Maxillofac Chir Orale. 2013 Dec;114(6):356-9. doi: 10.1016/j.revsto.2013.07.007. Epub 2013 Aug 22.
INTRODUCTION
Carcinosarcoma is a very rare malignant tumor of the salivary glands including accessory salivary gland, associating malignant mesenchymal and epithelial tissue. It usually occurs after 50 years of age. Its prognosis is very poor. We present a case of carcinosarcoma having evolved extremely rapidly.
CASE REPORT
A 38-year-old female patient presented with an inflammatory budding lesion of the mandibular gingival mucosa. The diagnosis of carcinosarcoma having developed from an accessory salivary gland was made after testing biopsies. The carcinosarcoma could not be removed because of an extremely rapid tumor growth, its volume having increased three fold in 2 weeks. The patient died in a few weeks.
DISCUSSION
The occurrence of carcinosarcoma at 38 years of age is exceptionally rare. The rapidly evolution of carcinosarcoma is well documented. It may prevent complete excision. This case led us to suggest an emergency management for carcinosarcomas.
引言
癌肉瘤是一种非常罕见的唾液腺恶性肿瘤，包括副唾液腺，由恶性间充质和上皮组织组成。它通常发生在50岁以后。其预后非常差。我们报告一例进展极其迅速的癌肉瘤病例。
病例报告
一名38岁女性患者，下颌牙龈黏膜出现炎性芽状病变。活检检测后诊断为源自副唾液腺的癌肉瘤。由于肿瘤生长极其迅速，癌肉瘤无法切除，其体积在2周内增加了两倍。患者在几周内死亡。
讨论
38岁发生癌肉瘤极为罕见。癌肉瘤的快速进展有充分记录。这可能会妨碍完全切除。该病例促使我们提出癌肉瘤的紧急处理方法。
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