Garner S L, Robinson R A, Maves M D, Barnes C H
Department of Otolaryngology-Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City.
Ann Otol Rhinol Laryngol. 1989 Aug;98(8 Pt 1):611-4. doi: 10.1177/000348948909800808.
True malignant mixed tumor, or carcinosarcoma, of salivary gland origin is rare. Only 19 cases have been reported in the literature and a review of cases seen at the University of Iowa over the last 60 years yielded only two. In one case the mesenchymal component of the tumor contained both osteosarcoma and chondrosarcoma. In the second case, the history and the histology suggest a progression from carcinoma ex pleomorphic adenoma to a carcinosarcoma. These features are documented in this report and literature review.
起源于涎腺的真性恶性混合瘤，即癌肉瘤，非常罕见。文献中仅报道过19例，对爱荷华大学过去60年所见病例的回顾仅发现2例。其中1例肿瘤的间叶成分包含骨肉瘤和软骨肉瘤。在第2例中，病史和组织学表现提示肿瘤由多形性腺瘤恶变而来，进而发展为癌肉瘤。本报告及文献综述记录了这些特征。
