Department of Dermatology, Skin and Laser Clinic, Hyderabad, India.
Indian J Dermatol Venereol Leprol. 2013 Jul;79 Suppl 7:S10-7. doi: 10.4103/0378-6323.115506.
Moderate to severe psoriasis is associated with concomitant diseases that may have a significant impact on patients. It is necessary for the treating physician to recognize these concomitant diseases, known as comorbidities, early as they influence the management options. Important comorbidities are psoriatic arthritis, metabolic syndrome, Crohn's disease, depression, and cancer. Patients with severe psoriasis may be at an increased risk for myocardial infarction and this subgroup of patients tends to have a reduced life expectancy. The presence of co-morbid diseases is associated with an increase in concomitant medication, some of which may worsen psoriasis; conversely, systemic treatment of psoriasis with certain drugs may impact the co-morbid conditions. As dermatologists are the primary health-care providers for psoriasis, adequate knowledge of comorbidities helps in choosing the appropriate therapy as well as timely intervention.
中重度银屑病常伴有合并症，这些合并症可能对患者产生重大影响。治疗医生需要尽早识别这些合并症，即合并疾病，因为它们会影响治疗方案的选择。重要的合并症包括银屑病关节炎、代谢综合征、克罗恩病、抑郁和癌症。重度银屑病患者可能有发生心肌梗死的风险增加，这类患者的预期寿命往往会缩短。合并疾病的存在与合并用药的增加有关，其中一些药物可能会使银屑病恶化；相反，某些药物治疗银屑病可能会对合并疾病产生影响。由于皮肤科医生是银屑病的主要医疗保健提供者，因此，充分了解合并症有助于选择适当的治疗方法和及时干预。
