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四种经皮肾镜取石术通道扩张方法的比较:系统评价和荟萃分析。

A comparison among four tract dilation methods of percutaneous nephrolithotomy: a systematic review and meta-analysis.

机构信息

Department of Urology, West China Hospital, Sichuan University, Guoxue Xiang #37, Chengdu, Sichuan, 610041, People's Republic of China.

出版信息

Urolithiasis. 2013 Nov;41(6):523-30. doi: 10.1007/s00240-013-0598-z. Epub 2013 Aug 23.

Abstract

The purpose of this study was to evaluate the efficacy and safety of the Amplatz dilation (AD), metal telescopic dilation (MTD), balloon dilation (BD), and one-shot dilation (OSD) methods for tract dilation during percutaneous nephrolithotomy (PCNL). Relevant eligible studies were identified using three electronic databases (Medline, EMBASE, and Cochrane CENTRAL). Database acquisition and quality evaluation were independently performed by two reviewers. Efficacy (stone-free rate, surgical duration, and tract dilatation fluoroscopy time) and safety (transfusion rate and hemoglobin decrease) were evaluated using Review Manager 5.2. Four randomized controlled trials and eight clinical controlled trials involving 6,820 patients met the inclusion criteria. The pooled result from a meta-analysis showed statistically significant differences in tract dilatation fluoroscopy time and hemoglobin decrease between the OSD and MTD groups, which showed comparable stone-free and transfusion rates. Significant differences in transfusion rate were found between the BD and MTD groups. Among patients without previous open renal surgery, those who underwent BD exhibited a lower blood transfusion rate and a shorter surgical duration compared with those who underwent AD. The OSD technique is safer and more efficient than the MTD technique for tract dilation during PCNL, particularly in patients with previous open renal surgery, resulting in a shorter tract dilatation fluoroscopy time and a lesser decrease in hemoglobin. The efficacy and safety of BD are better than AD in patients without previous open renal surgery. The OSD technique should be considered for most patients who undergo PCNL therapy.

摘要

本研究旨在评估经皮肾镜碎石术(PCNL)中使用 Amplatz 扩张(AD)、金属伸缩扩张(MTD)、球囊扩张(BD)和一次性扩张(OSD)方法进行通道扩张的疗效和安全性。使用三个电子数据库(Medline、EMBASE 和 Cochrane CENTRAL)来确定相关的合格研究。数据库采集和质量评估由两名审查员独立进行。使用 Review Manager 5.2 评估疗效(无结石率、手术时间和通道扩张透视时间)和安全性(输血率和血红蛋白下降)。四项随机对照试验和八项临床对照试验共纳入 6820 例患者符合纳入标准。荟萃分析的汇总结果显示,OSD 和 MTD 组在通道扩张透视时间和血红蛋白下降方面存在统计学差异,两组的无结石率和输血率相当。BD 和 MTD 组之间的输血率存在显著差异。对于无既往开放性肾手术的患者,与 AD 相比,BD 组的输血率更低,手术时间更短。与 MTD 技术相比,OSD 技术在 PCNL 中进行通道扩张时更安全、更有效,特别是对于既往有开放性肾手术史的患者,可缩短通道扩张透视时间,减少血红蛋白下降。BD 在无既往开放性肾手术史的患者中的疗效和安全性优于 AD。对于大多数接受 PCNL 治疗的患者,应考虑使用 OSD 技术。

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