值此动脉粥样硬化脂质假说诞生 100 周年之际。
In celebration of the 100th anniversary of the lipid hypothesis of atherosclerosis.
机构信息
University of California San Diego, La Jolla, CA 92093.
出版信息
J Lipid Res. 2013 Nov;54(11):2946-9. doi: 10.1194/jlr.R043414. Epub 2013 Aug 23.
Abstract
This year marks the 100th anniversary of the publication of Anitschkow's classic paper proposing the central role of hypercholesterolemia in atherogenesis. We at the Journal of Lipid Research take this occasion to acknowledge the debt we all owe to Anitschkow and his colleagues for getting us on the right track. As discussed below in detail, his contributions were insightful and went well beyond simply pinpointing hypercholesterolemia as a major etiologic factor. Anitschkow's work led him to define most of the key elements in the initiation and evolution of lesions in animal models of atherogenesis.
摘要
今年是 Anitschkow 发表经典论文提议高胆固醇血症在动脉粥样形成中的核心作用 100 周年。我们《脂质研究杂志》借此机会向 Anitschkow 和他的同事们表示感谢，感谢他们让我们走上了正确的道路。正如下面详细讨论的那样，他的贡献具有深刻的见解，远远超出了简单地指出高胆固醇血症是主要病因因素。Anitschkow 的工作使他定义了动脉粥样形成动物模型中病变起始和演变的大部分关键因素。
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