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Editorial: New trends in vascular biology 2024.社论：2024年血管生物学新趋势
Front Cardiovasc Med. 2025 Jul 24;12:1649558. doi: 10.3389/fcvm.2025.1649558. eCollection 2025.
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Vascular inflammation in chronic kidney disease: the role of uremic toxins in macrophage activation.慢性肾脏病中的血管炎症：尿毒症毒素在巨噬细胞激活中的作用。
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本文引用的文献

1
Cellular Heterogeneity of Activated Primary Human Macrophages and Associated Drug-Gene Networks: From Biology to Precision Therapeutics.活化原代人巨噬细胞的细胞异质性及其相关药物-基因网络：从生物学到精准治疗。
Circulation. 2023 Nov 7;148(19):1459-1478. doi: 10.1161/CIRCULATIONAHA.123.064794. Epub 2023 Oct 18.
2
Systems immunology-based drug repurposing framework to target inflammation in atherosclerosis.基于系统免疫学的药物再利用框架，用于靶向动脉粥样硬化中的炎症。
Nat Cardiovasc Res. 2023 Jun;2(6):550-571. doi: 10.1038/s44161-023-00278-y. Epub 2023 Jun 8.
3
Tissue-specific macrophages: how they develop and choreograph tissue biology.组织特异性巨噬细胞：它们如何发育以及协调组织生物学。
Nat Rev Immunol. 2023 Sep;23(9):563-579. doi: 10.1038/s41577-023-00848-y. Epub 2023 Mar 15.
4
Multiomics Network Medicine Approaches to Precision Medicine and Therapeutics in Cardiovascular Diseases.多组学网络医学在心血管疾病精准医学和治疗中的应用。
Arterioscler Thromb Vasc Biol. 2023 Apr;43(4):493-503. doi: 10.1161/ATVBAHA.122.318731. Epub 2023 Feb 16.
5
Translational opportunities of single-cell biology in atherosclerosis.单细胞生物学在动脉粥样硬化中的转化机会。
Eur Heart J. 2023 Apr 7;44(14):1216-1230. doi: 10.1093/eurheartj/ehac686.
6
Macrophages in health and disease.巨噬细胞在健康与疾病中的作用
Cell. 2022 Nov 10;185(23):4259-4279. doi: 10.1016/j.cell.2022.10.007.
7
Integrating multiplex immunofluorescent and mass spectrometry imaging to map myeloid heterogeneity in its metabolic and cellular context.整合多重免疫荧光和质谱成像技术，以在代谢和细胞环境中绘制髓系异质性图谱。
Cell Metab. 2022 Aug 2;34(8):1214-1225.e6. doi: 10.1016/j.cmet.2022.06.012. Epub 2022 Jul 19.
8
How Single-Cell Technologies Have Provided New Insights Into Atherosclerosis.单细胞技术如何为动脉粥样硬化提供新的见解。
Arterioscler Thromb Vasc Biol. 2022 Mar;42(3):243-252. doi: 10.1161/ATVBAHA.121.315849. Epub 2022 Feb 3.
9
Systems Approach to Discovery of Therapeutic Targets for Vein Graft Disease: PPARα Pivotally Regulates Metabolism, Activation, and Heterogeneity of Macrophages and Lesion Development.系统方法发现静脉移植物疾病的治疗靶点：PPARα 关键调节巨噬细胞的代谢、激活和异质性以及病变发展。
Circulation. 2021 Jun 22;143(25):2454-2470. doi: 10.1161/CIRCULATIONAHA.119.043724. Epub 2021 Apr 6.
10
Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2.单细胞蛋白质组学和转录组学分析使用 SCoPE2 分析巨噬细胞异质性。
Genome Biol. 2021 Jan 27;22(1):50. doi: 10.1186/s13059-021-02267-5.

Decoding Macrophage Heterogeneity to Unravel Vascular Inflammation as a Path to Precision Medicine.

作者信息

Chelvanambi Sarvesh, Decano Julius L, Winkels Holger, Giannarelli Chiara, Aikawa Masanori

机构信息

Center for Interdisciplinary Cardiovascular Sciences, Cardiovascular Division, Department of Medicine (S.C., J.L.D., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

Faculty of Medicine and University Hospital Cologne, Clinic III for Internal Medicine (H.W.), University of Cologne, Germany.

出版信息

Arterioscler Thromb Vasc Biol. 2024 Nov;44(11):2253-2257. doi: 10.1161/ATVBAHA.124.319571. Epub 2024 Oct 23.

DOI:10.1161/ATVBAHA.124.319571
PMID:39441912
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11715277/
Abstract
摘要