Rahman Adam, Martin Claudio, Heyland Daren K
Department of Medicine, University of Western Ontario, London, Ontario, Canada St. Joseph's Healthcare Centre/London Health Sciences Centre, London, Ontario, Canada.
Department of Medicine, University of Western Ontario, London, Ontario, Canada Critical Care/Trauma Centre, London Health Sciences Centre, Victoria Campus, London, Ontario, Canada Lawson Health Research Institute, London, Ontario, Canada.
JPEN J Parenter Enteral Nutr. 2015 Jan;39(1):104-13. doi: 10.1177/0148607113501695. Epub 2013 Aug 23.
Our goal is to define nutrition therapy in critically ill patients after surgical repair of acute ruptured or dissecting aortic aneurysm to identify opportunities for quality improvement.
International, prospective studies in 2007-2009 and 2011 were combined. Sites provided institutional and patient characteristics including from intensive care units (ICUs) admission to ICU discharge for a maximum of 12 days. We selected patients with aortic aneurysmal rupture or acute dissection staying in the ICU for ≥ 3 days.
There were 104 eligible patients from 72 distinct ICUs analyzed. Overall, 86.5% received artificial nutrition. There were 50.0% patients who received enteral nutrition (EN) only, 29.8% patients received a combination of EN and parenteral nutrition (PN), 6.7% patients received PN only, and 13.5% did not receive any nutrition. The mean time from admission to initiation of EN was 3.0 days (SD ± 2.4 days). The adequacy of calories from nutrition support was 46.8% (range 0%-111%) with a mean of 10.0 kcal/kg/day. Of the total of 83 patients who received EN, 53 patients (63.8%) had interruption of EN. The reasons included fasting, intolerance, patients deemed too sick for enteral feeding, and loss of enteral feeding route. For patients with gastrointestinal intolerance, 3/30 patients (10%) received small bowel feeding and 23/30 patients (76.7%) of patients received motility agents.
Postoperative critically ill patients with aortic aneurysmal rupture or acute dissection are at high risk for inadequate nutrition therapy, and there may be inadequate utilization of strategies to improve nutrition uptake.
我们的目标是明确急性破裂或夹层主动脉瘤手术修复后重症患者的营养治疗方法,以确定质量改进的机会。
将2007 - 2009年和2011年的国际前瞻性研究合并。各研究点提供了机构和患者特征,包括从重症监护病房(ICU)入院到ICU出院,最长12天。我们选择了在ICU停留≥3天的主动脉瘤破裂或急性夹层患者。
分析了来自72个不同ICU的104例符合条件的患者。总体而言,86.5%的患者接受了人工营养。仅接受肠内营养(EN)的患者占50.0%,接受EN和肠外营养(PN)联合治疗的患者占29.8%,仅接受PN的患者占6.7%,13.5%的患者未接受任何营养治疗。从入院到开始EN的平均时间为3.0天(标准差±2.4天)。营养支持的热量充足率为46.8%(范围0% - 111%),平均为10.0千卡/千克/天。在总共83例接受EN的患者中,53例(63.8%)出现EN中断。原因包括禁食、不耐受、患者病情过重无法进行肠内喂养以及肠内喂养途径丧失。对于胃肠道不耐受的患者,30例中有3例(10%)接受小肠喂养,30例中有23例(76.7%)接受促动力药物治疗。
急性主动脉瘤破裂或急性夹层术后的重症患者营养治疗不足的风险很高,且改善营养摄取的策略可能未得到充分利用。